The study's findings provide insights into the surprising evolution of proteins
A team of researchers from the Faculty of Science at Charles University, BIOCEV and IOCB (Czech Republic), Johns Hopkins University (USA) and ELSI (Japan) has discovered why modern proteins use a quasi-universal repertoire of 20 canonical amino acids (AAs). The study, published in the journal JACS, shows that foldability was likely a critical factor in the selection of the canonical alphabet.
Published Feb 28, 2023