Due to the GDPR guidlelines, the names of the respective students and supervisors are not listed here, only the titles of the respective theses (along with links to them in the Charles University Digital Repository, where you can find all relevant information). The theses are categorized according to the supervisor's institution and, within each institution, are sorted alphabetically. The majority of theses are written in Czech but all have at least an English abstract. Information on the current and past supervisory activities of individual internal members of the Department of Genetics and Microbiology can be found on the websites of the respective Laboratories.
Department of Genetics and Microbiology, Faculty of Science, Charles University
- Analysis of different forms of autophagy in differentiated cells of yeast colonies
- Development of DNA vaccine against fish orthoreovirus 3 (PRV3)
- Impact of selected transcription factors on ATO3 gene expression
- Introducing of an experimental approach to study mitotic translation in human cell lines
- Long term sublethal stress in colonies of Saccharomyces cerevisiae deleted in WHI3
- Protein STING and its regulation during polyomavirus infection
- Studies on the mechanisms of activation of the DNA sensor p204 during Mouse polyomavirus infection
- Study of cellular innate immune response to BK polyomavirus replication
- The effect of topoisomerase inhibitors on the activation of the DNA sensor cGAS
Institute of Microbiology of the Czech Academy of Sciences
- Effect of Kingella kingae and its RtxA cytotoxin on innate immune response
- Factors contributing to stress adaptation of human pathogen Bordetella pertussis
- Investigation of HSP70 oligomerization by structural mass spectrometry
- Regulation of transcription in Streptococcus pneumoniae
- The interplay between StkP-directed phosphorylation and catabolic repression in Streptococcus pneumoniae
- The interplay between StkP/PhpP phosphorylation pathway and diadenylate cyclase CdaA producing c-di-AMP in Streptococcus pneumoniae
- The role of LmbF and CcbF proteins in the biosynthesis of the antibiotics lincomycin and celesticetin and their potential application in the biosynthesis of the hybrid antibiotic CELIN
- The role of ribosomal proteins in accommodation of near-cognate tRNAs during stop codon readthrough
Institute of Molecular Genetics of the Czech Academy of Sciences
Institute of Physiology of the Czech Academy of Sciences
- Glucose effect on lipid metabolism homeostasis in pancreatic β-cells
- Role of glucocorticoids in synchronization of fetal suprachiasmatic nuclei
- Study of the biogenesis of monovalent-cation transporters in eukaryotic cell
- The impact of post-translational modifications on TRPC5 ion channel activation and modulation
Institute of Hematology and Blood Transfusion
Faculties of Medicine, Charles University
- Frequency and relevance of chromosome 17 aberrations in adult patients with myelodysplastic syndromes (MDS)
- Identification of new tissue-specific interaction partners of chromatin remodelling ATPase Smarca5
- Investigation of the role of the KEAP1-NRF2 antioxidant pathway in the therapy of secondary acute myeloid leukemia
- Structure and function of the ribosomal intergenic DNA
- The development of genetic and epigentic aberrations in patients with recurrent cerebral gliomas
Other Departments of the Faculty of Science, Charles University
- Effects of microplastics on earthworm gut microbiome, their immunity system and metabolome
- Exploration of tryptophan in/dispensability in Escherichia coli by recombineering