Due to the GDPR guidlelines, the names of the respective students and supervisors are not listed here, only the titles of the respective theses (along with links to them in the Charles University Digital Repository, where you can find all relevant information). The theses are categorized according to the supervisor's institution and, within each institution, are sorted alphabetically. The majority of theses are written in Czech but all have at least an English abstract. Information on the current and past supervisory activities of individual internal members of the Department of Genetics and Microbiology can be found on the websites of the respective Laboratories.

 

Department of Genetics and Microbiology, Faculty of Science, Charles University

4E translation initiation factors and their influence on regulation of gene expression

Dynamics of yeast colony differentiation: New approaches

Effect of polyhistidine modification of viral particles on their intracellular localization and gene delivery to the nucleus

Interaction of Whi3 and Yap6 under mild osmotic stress

Major capsid protein of polyomaviruses and its interactions with nuclear lamins

Preparation and validation of a system for the study of regulation of gene expression of yeast linear cytoplasmic plasmids

Study of persistence mechanisms to antibiotics in Staphylococcus aureae

The role of histone deacetylase 6 in murine polyomavirus replication cycle

 

Institute of Microbiology of the Czech Academy of Sciences

Cysteine tRNA regulates protein synthesis in human cell lines

Mechanism of inducible gene expression of resistance protein Vga(A)LC from Staphylococcus haemolyticus

Production of toxins by Bacillus subtilis and their roles in interspecies competitions

Regulation of penicillin-binding protein Pbp2a in Streptococcus pneumoniae

SigN from Bacillus subtilis: Functional characterization

Study of the unique signaling pathway of Ser/Thr protein kinase StkP and phosphatase PhpP in Streptococcus pneumoniae

 

Institute of Molecular Genetics of the Czech Academy of Sciences

Cancerogenic and metastatic potential of cancer cells with non-functional CRL4 ubiquitination complex

Determinants of fusogenicity of Syncytin-1, cellular glycoprotein of retroviral origin

Meiotic effect of MutS homolog 6 (Msh6) mutation in two mouse subspecies

 

Institute of Biotechnology of the Czech Academy of Sciences

Characterization of a role of selected antiapoptotic Bcl-2 family proteins in mitochondrial metabolism

Proteins mimicking epitopes of broadly neutralizing HIV-1 antibodies

 

Institute of Experimental Medicine of the Czech Academy of Sciences

The role of DNA repair pathways in ovarian cancer therapy response

 

Institute of Physiology of the Czech Academy of Sciences

Detection of genetic modifications associated with pancreatic adenocarcinoma

 

Institute of Animal Physiology and Genetics of the Czech Academy of Sciences

Analysis of karyotype and sex chromosome differentiation in African annual killifish of the genus Nothobranchius (Teleostei: Nothobranchiidae)

 

National Institute of Public Health

New molecular biomarkers and therapeutical targets in solid tumors

 

Faculties of Medicine, Charles University

Aberrations of chromosome 5 in adult patients with myelodysplastic syndromes (MDS)

Analysis of methicillin resistant Staphylococcus aureus strains from Czech Republic and Slovakia

Characterization of newly developed fluorescence probes in cellular systems

Interaction of human immune cells with ultrasmall nanoparticles

Next generation sequencing in clinical virology: method optimization and it's use for samples with unknown infectious agent

Postpartum expression of cardiovascular disease-associated microRNAs - comparison of expression levels between plasma, plasma exosomes and whole peripheral venous blood

Re-analysis of suspected patients with FAP disease (Familial adenomatous polyposis)

The stool bacteriome during therapy for paediatric non-infectious diseases