Due to the GDPR guidelines, the names of the respective students and supervisors are not listed here, only the titles of the respective theses (unfortunately, these older theses are not available in electronic forms). The theses are categorized according to the supervisor's institution and, within each institution, are sorted alphabetically. The absolute majority of theses were written in Czech. Information on the current and past supervisory activities of individual internal members of the Department of Genetics and Microbiology can be found on the websites of the respective Laboratories.

Department of Genetics and Microbiology, Faculty of Science, Charles University

  • Adaptation of the Bacillus subtilis 168trp2- bacterial membrane to ethanol stress
  • Adaptation of the Bacillus subtilis 168trp2- cytoplasmic membrane to detergents
  • Artificial capsids of mouse polyomavirus and their interaction with the host cell
  • Impact of polyomavirus and its structural protein VP1 on the cytoskeleton and organization of selected nuclear proteins
  • Inheritance of photosynthetic characteristics in maize (Zea mays L.) grown at low temperatures
  • Interaction of the major capsid protein of polyomavirus with cellular structures of Saccharomyces cerevisiae
  • Morphogenesis of yeast colonies: role of Gpa2 protein in NH3 signaling; using GFP protein to monitor CAT2 gene expression

Institute of Microbiology of the Czech Academy of Sciences

  • Acetolactate synthase in Streptomyces cinnamonensis
  • Analysis of promoter activity regulation of the per gene on plasmid pGA1 from Corynebacterium glutamicum
  • Detection of the mecA gene in methicillin-resistant staphylococci
  • Genomic characterization of a probiotic strain Escherichia coli O83:K24:H31
  • Impact of heavy metals on nitrogen and sulfur metabolism in wood-decaying fungi
  • Natural humoral immunity in annelids
  • Regulation of gene expression in the leucine biosynthesis pathway
  • Study of LmbQ and LmbE proteins – potential subunits of N-demethyllincomycin synthase
  • Targeted modification of the gene encoding N-demethyllincomycin methyltransferase

Institute of Molecular Genetics of the Czech Academy of Sciences

  • Alteration of phosphorylation of the eukaryotic initiation factor 2 in normal and cancer cells
  • Methylation of regulatory sequences in LTR retroviruses integrated into vertebrate genomes
  • Search for genes controlling mouse response to infection with the parasitic protozoan Leishmania major
  • Tissue distribution and development changes in expression of a novel glycosylphosphatidyl inositol-anchored protein, TEC-21

Institute of Physiology of the Czech Academy of Sciences

  • Molecular mechanisms of circadian rhythms: effect of natural summer and winter photoperiods on rhythmic rPER1 protein production in rat SCN; effect of artificial long and short photoperiods on rhythmic rBma1 mRNA production in rat SCN; splicing variants of the clock gene rBma1
  • Physiological characterization of the osmotolerant yeast Zygosaccharomyces rouxii and optimization of its transformation protocol

Institute of Animal Physiology and Genetics of the Czech Academy of Sciences

  • Variability of chromosomal features in three species of gudgeons of the genera Gobio and Romanogobio (Cyprinidae, Actinopterygii)

Institute of Hematology and Blood Transfusion

  • Utilization of mtDNA variability as a marker in monitoring cell chimerism after bone marrow transplantation

National Institute of Public Health

  • Implementation and use of the PCR method in the diagnosis of Chlamydia pneumoniae

Faculties of Medicine, Charles University

  • Implementation of apolipoprotein (a) genotyping
  • Quantitative detection of WT1 gene expression in pediatric acute myeloid leukemia: prognostic significance and monitoring of residual disease
  • Utilization of comparative PCR in monitoring B-lymphoproliferative disorders
  • Utilization of new methods in prenatal diagnosis of the most common chromosomal aberrations
  • Utilization of QF-PCR (quantitative fluorescent polymerase chain reaction) in diagnosing the most common aneuploidies

Crop Research Institute

  • Targeted mutagenesis of the phosphofructokinase gene from Lactobacillus bulgaricus