Due to the GDPR guidelines, the names of the respective students and supervisors are not listed here, only the titles of the respective theses (unfortunately, these older theses are not available in electronic forms). The theses are categorized according to the supervisor's institution and, within each institution, are sorted alphabetically. The absolute majority of theses were written in Czech. Information on the current and past supervisory activities of individual internal members of the Department of Genetics and Microbiology can be found on the websites of the respective Laboratories.


Department of Genetics and Microbiology, Faculty of Science, Charles University

  • Communication between yeast colonies
  • Development and communication of yeast colonies: identification of genes variably expressed during colony morphogenesis
  • Expression of mutated genes for the major structural protein VP1 of mouse polyomavirus in insect cells
  • Linear plasmids of yeasts
  • Structure and function of the major capsid protein VP1 in polyomaviruses
  • Study of adenylate cyclase toxin of Bordetella pertussis using fluorescence methods
  • Study of interactions between the major capsid protein VP1 of polyomavirus and yeast proteins

Institute of Microbiology of the Czech Academy of Sciences

  • Characterization of serine/threonine protein kinases in Streptomyces granaticolor
  • Study of adenylate cyclase toxin and its interactions with target membranes using electron microscopy techniques
  • Study of membrane topology of adenylate cyclase toxin from Bordetella pertussis using inserted FLAG epitopes

Institute of Molecular Genetics of the Czech Academy of Sciences

  • Fine genetic analysis of the Hst1 region on mouse chromosome 17
  • Induction of apoptosis by iron deprivation and expression of Bcl-2 family proteins

Institute of Experimental Medicine of the Czech Academy of Sciences

  • Analysis of DNA adducts of polycyclic aromatic compounds and their derivatives
  • Kinetics of DNA damage in blood cells of chicken embryos after exposure to embryotoxic doses of 1,2-dibromoethane
  • Morphogenesis of embryonic kidney after exposure of chicken embryos to xenobiotics: effects of 1,2-dibromoethane and cis-diamminedichloroplatinum

Institute of Hematology and Blood Transfusion

  • Cervical carcinoma - HPV as an etiological factor and tumor markers
  • Construction of recombinant vaccinia virus for studying antitumor immunity against HPV 16-induced tumors

Institute of Endocrinology

  • Senile form of Alzheimer's disease: study of genes for apolipoprotein E and amyloid precursor protein

National Institute of Public Health

  • Analysis of genotypes of biotransformation enzymes in selected population groups

Faculties of Medicine, Charles University

  • Detection of mutations and polymorphisms in the CFTR gene in patients with reproductive disorders
  • Detection of numerical abnormalities of sex chromosomes by fluorescence in situ hybridization
  • Microsatellite instability and loss of heterozygosity on chromosome 16 in patients with Wilms' tumor
  • Monitoring of mutations in the CFTR gene
  • Mutator phenotype of colorectal cancer cells
  • Semiquantitative monitoring of molecular markers in patients with non-Hodgkin lymphoma
  • Targeted polymeric drugs based on poly(HPMA) with antitumor activity

Institute of Animal Science

  • Estimation of genetic effects from diallel analysis of photosynthetic pigment content in maize (Zea mays L.) leaves