Due to the GDPR guidlelines, the names of the respective students and supervisors are not listed here, only the titles of the respective theses (along with links to them in the Charles University Digital Repository, where you can find all relevant information). The theses are categorized according to the supervisor's institution and, within each institution, are sorted alphabetically. The majority of theses are written in Czech but all have at least en English abstract. Information on the current and past supervisory activities of individual internal members of the Department of Genetics and Microbiology can be found on the websites of the respective Laboratories.

 

Department of Genetics and Microbiology, Faculty of Science, Charles University

Adaptor protein STING and his role in viral infections

Annulate lamellae and their role in viral infection

Autophagy in viral infections of small unenveloped DNA viruses, with the focus on the roles of autophgy in infection by DNA viruses

Bacteriocins produced by gram-negative bacteria with a focus on microcins - their mechanism of action

Chromatin modifications and small regulatory RNA in plant intergenerational and transgenerational stress memory: experiments in plants subjected to drought

Evolution of telomeric motif in arthropods

HPV variants and their association with diseases

Karyotype evolution of cobweb spiders (Araneae: Theridiidae)

Microbiome and its changes in patients with psoriasis

Role of cGAS-STING pathway in tumour suppression and tumorigenesis

The role of infection of HPV and EBV in the etiology of nasopharyngeal and cervical carcinoma

Torque teno virus - a marker of immune function

Virome of European bats

Viruses and autoimmune diseases

Virus interaction with the cellular DNA damage response

Yeast as a tool for synthetic biology

 

Institute of Microbiology of the Czech Academy of Sciences

Antimicrobial peptides inhibiting DNA synthesis

DNA topology as a factor affecting transcription in bacteria

Effect of oxidative stress on mitochondria

Secondary metabolites from Chaetosphaeriaceae

 

Institute of Molecular Genetics of the Czech Academy of Sciences

Genetic rodent models of human non-syndromic secondary premature ovarian insufficiency

Utilizing single-cell RNA sequencing and spatial transcriptomics in the study of neurodegenerative diseases

 

Institute of Biotechnology of the Czech Academy of Sciences

Cell-cell communication analysis in single-cell and spatial transcriptomics

 

Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences

Mechanisms of membrane protein quality control in the endoplasmic reticulum

 

Institute of Physiology of the Czech Academy of Sciences

Role of melatonin in the mammalian intestine and its interaction with the gut microbiome

 

Institute of Haematology and Blood Transfusion

Using CRISPR-Cas9 gene editing to engineer the next generation of CAR T cells

 

Faculties of Medicine, Charles University

Context-dependent roles of cyclin-dependent kinase inhibitors (CDKi) in cancer

 

Other Supervisory Institutions

Microbial Forensics

The comparison of animal species determination (barcoding) methods

The testing of familiar relationship in the identification genetics