B.Sc. Theses Successfully Defended in the Academic Year 2022/2023

Due to the GDPR guidlelines, the names of the respective students and supervisors are not listed here, only the titles of the respective theses (along with links to them in the Charles University Digital Repository, where you can find all relevant information). The theses are categorized according to the supervisor's institution and, within each institution, are sorted alphabetically. The majority of theses are written in Czech but all have at least an English abstract. Information on the current and past supervisory activities of individual internal members of the Department of Genetics and Microbiology can be found on the websites of the respective Laboratories.

Department of Genetics and Microbiology, Faculty of Science, Charles University

• Adaptive immune response against BK polyomavirus infection
• Functions of open MHC class I molecule conformations
• Micronuclei and their connection with intracellular innate immunity and viral infection
• Molecular analysis of Cornelia de Lange syndrom
• Non-template activities of DNA/RNA polymerases and their significance
• Oral microbiome and carcinogenesis
• Role of Zinc-α2-glycoprotein in tumors
• The evolution of SARS-CoV-2 virus during the pandemic of COVID-19
• The importance of cell-free HPV DNA detection
• The role of IFI16 protein in viral infection
• The role of small RNAs in transgenerational plant stress memory

Institute of Microbiology of the Czech Academy of Sciences

• Post-transcriptional modification of mRNA molecules in viruses of the Poxviridae family
• Structural-functional aspects of the Bordetella pertussis adenylate cyclase toxin
• Where transcription meets translation

Institute of Molecular Genetics of the Czech Academy of Sciences

• In vitro models for studying Syncytin-1-induced fusion of trophoblast cells
• Tcf4 transcription factor in the intestinal epithelium renewal and pathologyi
• The impact of chimerism in DNA-based forensic analysis

Institute of Biotechnology of the Czech Academy of Sciences

• Molecular mechanisms in the development of the cochlea

Institute of Experimental Medicine of the Czech Academy of Sciences

• The role of a specific miRNAs in the regulation of apoptosis during physiological and pathophysiological processes in the CNS

Institute of Animal Physiology and Genetics of the Czech Academy of Sciences

• Current genomic and cytogenomic methods in analysis of chromosome rearrangements

Faculties of Medicine, Charles University

• Global epidemiology of Staphylococcus aureus circulating in healthcare system and community
• Regulation of histone post-translational modifications and its use in the diagnosis and treatment of lung cancer

Other Supervisory Institutions

• Motility and virulence of bacterial pathogens in patients with cystic fibrosis
• Sampling of biological material for forensic examinations