Ph.D. Theses Successfully Defended in the Academic Year 2019/2020

Due to the GDPR guidlelines, the names of the respective students and supervisors are not listed here, only the titles of the respective theses (along with links to them in the Charles University Digital Repository, where you can find all relevant information). The theses are categorized according to the supervisor's institution and, within each institution, are sorted alphabetically. Some theses are written in Czech but all have at least an English abstract. Information on the current and past supervisory activities of individual internal members of the Department of Genetics and Microbiology can be found on the websites of the respective Laboratories.

Department of Genetics and Microbiology, Faculty of Science, Charles University

• Characterization of non-canonical RNA polymerase encoded by the yeast linear plasmids
• Noncanonical functions of IL-1α
• Noncanonical human eIF4Es in and out of the RNA granules

Institute of Microbiology of the Czech Academy of Sciences

• Analysis of signaling cascade of protein kinase StkP in Streptococcus pneumoniae
• Function of stress sigma factors of RNA polymerase SigD, SigE, SigH and SigM in transcription regulation network of Corynebacterium glutamicum
• The effect of selected endogenous and exogenous factors on bacterial growth
• The role of elF3 a Rps3 in stop codon readthrough

Institute of Molecular Genetics of the Czech Academy of Sciences

• TET1 overexpression, DNA hypomethylation and aberrant expression of human endogenous retrovirus ERVWE1 in germ cell tumors
• The role of ADAM17 and other metalloproteases in liver pathological processes
• The role of ORMDL proteins in mast cell signaling

Institute of Biotechnology of the Czech Academy of Sciences

• Functional role of SOX2 in inner ear neurosensory development
• Molecular mechanisms in transcriptional regulation of neurosensory development
• The role of nitric oxide during embryonic wound healing and regeneration

Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences

• Rhomboid family intramembrane proteases in prokaryotes: mechanism, substrate repertoires and biological functions in the Gram-positive bacterium Bacillus subtilis

Institute of Experimental Medicine of the Czech Academy of Sciences

• Changes in domain organization of the plasma membrane in the stress response
• The effect of air pollution on oxidative stress markers in newborns

Institute of Physiology of the Czech Academy of Sciences

• Molecular mechanisms of mammalian circadian clocks, its sensitivity to constant light and aging

Crop Research Institute

• Soil microbial communities in agroecosystems and natural habitats contributing to resistance and resilience of the soil environment