Due to the GDPR guidelines, the names of the respective students and supervisors are not listed here, only the titles of the respective theses (unfortunately, these older theses are not available in electronic forms). The theses are categorized according to the supervisor's institution and, within each institution, are sorted alphabetically. The absolute majority of these theses were written in Czech. Information on the current and past supervisory activities of individual internal members of the Department of Genetics and Microbiology can be found on the websites of the respective Laboratories.

Department of Genetics and Microbiology, Faculty of Science, Charles University

  • Changes in mitochondria and oxygen radicals during Saccharomyces cerevisiae colony development
  • Changes in production and expression of ATO transporters during yeast colony development and liquid cultures
  • Characterization of Saccharomyces cerevisiae mutants with altered alkalization ability
  • Membrane proteins of Bacillus subtillis 168trp2- after osmotic stress
  • Morphological and physiological analysis of colonies from wild strains of Saccharomyces cerevisiae
  • New DNA helicase encoded by linear plasmids pGKL
  • Study of minor structural proteins of mouse polyomavirus
  • Study of Saccharomyces cerevisiae mutants with altered sensitivity to killer toxins K1 and K2

Institute of Microbiology of the Czech Academy of Sciences

  • Biotransformation of nitriles into amides and acids by enzymes from filamentous fungi
  • Identification of genes involved in the biosynthesis of the lincosamide antibiotic celesticetin
  • Natural antioxidant defense during replicative and chronological aging of Saccharomyces cerevisiae
  • Searching for a nuclear transporter for Isw1p, a chromatin remodeling factor in Saccharomyces cerevisiae
  • Searching for interactions between selected proteins involved in lincomycin biosynthesis
  • The effect of ppk gene inactivation/overexpression in Streptomyces lividans

Institute of Molecular Genetics of the Czech Academy of Sciences

  • Analysis of methylation of 5'LTR of syncytin-human retroviral gene
  • Expression analysis of selected X-linked genes during mouse spermatogenesis
  • The ybxF gene - a new component of the streptomycin operon in Bacillus subtilis

Institute of Experimental Medicine of the Czech Academy of Sciences

  • Effect of intracellular parts of metabotropic glutamate receptor on interaction with G-protein, dimerization, and transport

Institute of Physiology of the Czech Academy of Sciences

  • Analysis of nuclear OXPHOS gene expression using real-time PCR
  • Construction and optimization of a mitochondrial chip
  • Expression of high-affinity choline transporter in neuroblastoma cells

Institute of Hematology and Blood Transfusion

  • Development of a recombinant vaccine against chronic myeloid leukemia
  • Study of gene expression during differentiation of leukemic cells

Institute of Clinical and Experimental Medicine

  • Molecular-genetic methods for investigating HLA polymorphism
  • Occurrence of null alleles of the HLA system in the Czech population

Faculties of Medicine, Charles University

  • Biochemical and molecular characterization of energy metabolism in cultured cell lines with A3243G and G3460A mutations in mitochondrial DNA
  • Complex karyotypic changes in patients with chronic myeloid leukemia
  • Expression of BCL-2 and BAX genes in relation to chemoresistance of cancer cells
  • Mutation analysis of the APC in patients with familial adenomatous polyposis
  • Mutations in mitochondrial DNA in patients with hypertrophic cardiomyopathy and energy metabolism disorders
  • Nijmegen breakage syndrome
  • Optimization of the TTGE method for detecting unknown mutations in the CFTR gene in cystic fibrosis