News

Dr. Jan Dobeš from the Department of Cell Biology at the Faculty of Science, Charles University, has received the prestigious Česká hlava award. He was awarded by the INVENTION prize for his outstanding achievement in the field of basic or applied research in the 23rd year of the competition.

Researchers have made a remarkable advancement in understanding how cells regulate their inner framework. The team from three institutes of the Czech Academy of Science, the Institute of Molecular Genetics, the Institute of Biotechnology and the Institute of Organic Chemistry and Biochemistry, the Faculty of Science of Charles University, BIOCEV and CEITEC has uncovered the precise molecular mechanisms behind the protein MICAL1, which plays a crucial role in maintaining cell shape and movement. Researchers' findings offer a detailed insight into MICAL1’s function in controlling actin filaments—the cell's flexible “skeleton”—and open up new possibilities for developing treatments to address diseases linked to MICAL dysfunction. The study was published by the prestigious journal Nature Communications.

Grant Agency of Czech Republic has announced the results of two grant schemes for excellent projects EXPRO and JUNIOR STAR for 202

Excited to share the latest research published in EMBO Molecular Medicine! Mašek and Andersson labs in collaboration with Björkström, Gregor and Dobeš labs explored the specific, pericellular fibrosis in Alagille syndrome (ALGS).

Congrats to the authors of the new paper AHoJ-DB: A PDB-wide Assignment of apo & holo Relationships Based on Individual Protein–Ligand Interactions

We congratulate to Farahdokht Nourisanami, Margarita Sobol and Zhuoran Li from Dan Rozbeský's lab for their paper on semaphorin signaling in axon guidance!