Detailed information about the study programme
Offer of dissertation topics:
- Analysis of the role of TRAK proteins in mitochondrial transport and neural development
- Brain mechanisms of cognitive biases
- Cellular senescence-associated cardiovascular and renal diseases in hypertensive rats.
- Characterization of neurodevelopmental diseases-associated NMDA receptor variants (GRIN genes) in the context of human genomes and their effects on the development and regulation of neuronal excitatory signalization
- Deciphering the role of bone marrow adipocytes in mouse models of obesity: impact of sex dimorphism
- Development of bioactive scaffolds for the wound healing
- Effect of genetic factors and perinatal programming on individual mechanisms of non-shivering thermogenesis in mice
- Enhancement of vascularized bone tissue formation using functionalized diamond scaffolds and electric stimulation
- Extracellular matrix modulation as a tool to influence pathological conditions in the CNS.
- In vivo and in vitro characterization of mechanisms of muscle non-shivering thermogenesis
- Mechanism of assembly of mitochondrial respiratory complex II
- Mechanism of centrobin function, the protein essential for sperm head coupling to flagellum.
- Mechanisms of protective effects of empagliflozin – the role of HIF-1α
- Mesenteric adipose tissue as part of the intestinal barrier in the progression of MASLD
- Modulation of inhibitory synaptic transmission at the spinal cord level in pathological pain conditions
- Modulation of Chondroitin Sulfate Sulfation Patterns to Support Neuroplasticity and Regeneration in Aging and Spinal Cord Injury
- Neuronal-type-specific targeting of nAChRs using a pair of nitroreductase and masked nicotinic ligands
- Nicotinic acetylcholine receptors in prefrontal neuronal populations and their role in the control of ASD-like behavioral symptoms
- Novel ways to allosteric modulation of muscarinic receptors
- Potential role of the adaptor GTPase Miro1 in cardiac function
- Rare disease-associated variants in NMDAR genes: impact on synaptic transmission and plasticity.
- Role of dystrophin-associated protein complex DAPC in thermoregulation of animal DMD models
- Role of efficiency of muscle contraction and non-shivering thermogenesis in protection against cold and obesity
- Targeted Modulation of NMDA Receptors: Personalized Therapeutics for CNS Disorders
- The role cytokines in neuroinflammation and nociception modulation
- The role of hypoxia-inducible factor-1alpha on the progression of heart failure with preserved ejection fraction.
- 11-Oxygenated androgens: description of physiological changes and their role in disorders of steroidogenesis
Profile of the graduate
Animal physiology graduate has advanced knowledge of animal and human biology, including a thorough knowledge of body structure and functions. He/she is familiar with integrative physiological functions of the whole organism and their regulations as well as with the molecular and cellular mechanisms underlying complex physiological processes. He/she also has a good undestanding of related disciplines such as cellular and molecular biology, biochemistry, pharmacology, toxikology and imunology. He/she is familiarized with physiological research methods and is capable of implementing them in biomedical sphere. His/her ability of abstract and creative thinking can be used in both basic or applied research at universities, in scientific institutes and biotechnological centres as well as in medical institutions and pharmaceutical industry.
Application submission
The application is submitted electronically through the Charles University study information system. The completed application must be submitted electronically in the study information system no later than on 30. 4. 2025 for study programmes starting in the winter semester (October) and no later than on 15. 12. 2025 for study programmes starting in the summer semester (April).
The admission fee is 100 EUR and it is paid for each submitted application.
Entrance exam
The regular date of entrance exam for all doctoral programmes starting in the winter semester (October) is 9. - 20. 6. 2025, an alternative date is 23. - 27. 6. 2025.
The regular date of entrance exam for all doctoral programmes starting in the summer semester (April) is 4. - 5. 2. 2026, an alternative date is 11. - 12. 2. 2026.
The request for an alternative day is submitted and approved via the electronic information system.
The form of the entrance exam is an oral interview, which mainly concerns the issues of the planned dissertation and the candidate's knowledge within the field of expertise of the given study programme.
Find more information in:
- Conditions of the admission procedure for doctoral study programmes at the Faculty of Science, Charles University, for study programmes starting in the winter semester (October)
or - Conditions of the admission procedure for doctoral study programmes at the Faculty of Science, Charles University, for study programmes starting in the summer semester (April).
Important links
Applicants with specific needs
If you have a physical handicap, you can apply for a modification of the entrance exam. For more information read the Conditions of the admission procedure for doctoral study programmes.
Departments involved in this programme
Guarantor of the study programme
doc. RNDr. Jiří Novotný, DSc.
jiri.novotny@natur.cuni.cz
Do you have a question?
Complete information about the admission procedure can be found on the website for applicants. For questions, please contact the admissions contact persons.