Publikace

Úplný přehled publikační činnosti katedry biochemie naleznete zde.

2023 (z celkového počtu 36)

Heames, B.; Buchel, F.; Aubel, M.; Treťjačenko, V.; Loginov, D.; Novák, P.; Lange, A.; Bornberg-Bauer, E.; Hlouchová, K.; Experimental characterization of de novo proteins and their unevolved random-sequence counterparts. NATURE ECOLOGY & EVOLUTION, 2023, Roč. 7, č. 4, s.570-580. IF=16.8 DOI: 10.1038/s41559-023-02010-2

Stolařová, L.; Kleiblová, P.; Zemánková, P.; Šťastná, B.; Janatová, M.; Soukupová, J.; Achatz, MI.; Ambrosone, Ch.; Apostolou, P.; Arun, BK.; Auer, P.; Barnard, M.; Bertelsen, B.; Japan, B.; Blok, MJ.; Boddicker, N.; Brunet, J.; Burnside, ES.; Calvello, M.; Campbell, I.; Chan, SH.; Chen, F.; Chiang, JB.; Coppa, A.; Cortesi, L.; Crujeiras-González, A.; Czecanca, C.; De Leeneer, K.; De Putter, R.; DePersia, A.; Devereux, L.; Domchek, S.; Efremidis, A.; Engel, Ch.; Ernst, C.; Evans, GD.; Feliubadaló, L.; Fostira, F.; Fuentes-Ríos, O.; Gómez-García, EB.; González, S.; Haiman, Ch.; van Overeem Hansen, T.; Hauke, J.; Hodge, J.; Hu, Ch.; Huang, H.; Binte Ishak, ND.; Iwasaki, Y.; Konstantopoulou, I.; Kraft, P.; Lacey, J.; Lázaro, C.; Li, N.; Lim, WK.; Lindstrom, S.; Lori, A.; Martinez, E.; Martins, A.; Matsuda, K.; Matullo, G.; McInerny, S.; Michailidou, K.; Montagna, M.; Monteiro, AN.; Mori, L.; Nathanson, K.; Neuhausen, SL.; Nevanlinna, H.; Olson, JE.; Palmer, J.; Pasini, B.; Patel, A.; Piane, M.; Poppe, B.; Radice, P.; Renieri, A.; Resta, N.; Richardson, ME.; Rosseel, T.; Ruddy, KJ.; Santamariña, M.; Dos Santos, ES.; Teras, L.; Toland, AE.; Trentham-Dietz, A.; Vachon, CM.; Volk, AE.; Weber-Lassalle, N.; Weitzel, JN.; Wiesmuller, L.; Winham, S.; Yadav, S.; Yannoukakos, D.; Yao, S.; Zampiga, V.; Zethoven, M.; Zhang, ZW.; Zima, T.; Spurdle, AB.; Vega, A.; Rossing, M.; Del Valle, J.; De Nicolo, A.; Hahnen, E.; Claes, KB.; Ngeow, J.; Momozawa, Y.; James, PA.; Couch, FJ.; Macůrek, L.; Kleibl, Z.; ENIGMA CHEK2gether Project: A Comprehensive Study Identifies Functionally Impaired CHEK2 Germline Missense Variants Associated with Increased Breast Cancer Risk. Clinical Cancer Research, 2023, Roč. 29, č. 16, s.3037-3050. IF=11.5 DOI: 10.1158/1078-0432.CCR-23-0212

Polák, M.; Palasser, M.; Kádek, A.; Kavan, D.; Wootton, ChA.; Delsuc, M.; Breuker, K.; Novák, P.; van Agthoven, MA.; Top-Down Proteoform Analysis by 2D MS with Quadrupolar Detection. Analytical Chemistry, 2023, Roč. 95, č. 44, s.16123-16130. IF=7.4 DOI: 10.1021/acs.analchem.3c02225

Hýsková, V.; Jakl, M.; Jaklová Dytrtová, J.; Zeljković, SĆ.; Vrobel, O.; Bělonožníková, K.; Kavan, D.; Křížek, T.; Šimonová, A.; Vašková, M.; Kovač, I.; Račko Žufić, A.; Ryšlavá, H.; Antifungal triazoles affect key non-target metabolic pathways in Solanum lycopersicum L. plants. Ecotoxicology and Environmental Safety, 2023, Roč. 268, č. neuvedeno, s.1-12. IF=6.8 DOI: 10.1016/j.ecoenv.2023.115729

Bělonožníková, K.; Černý, M.; Hýsková, V.; Synková, H.; Valcke, R.; Hodek, O.; Křížek, T.; Kavan, D.; Vaňková, R.; Dobrev, PI.; Haisel, D.; Ryšlavá, H.; Casein as protein and hydrolysate: Biostimulant or nitrogen source for Nicotiana tabacum plants grown in vitro? Physiologia Plantarum, 2023, Roč. 175, č. 4, IF=6.4 DOI: 10.1111/ppl.13973

Otáhalová, B.; Volková, Z.; Soukupová, J.; Kleiblová, P.; Janatová, M.; Vočka, M.; Macurek, L.; Kleibl, Z.; Importance of Germline and Somatic Alterations in Human MRE11, RAD50, and NBN Genes Coding for MRN Complex. International Journal of Molecular Sciences, 2023, Roč. 24, č. 6, IF=5.6 DOI: 10.3390/ijms24065612

Ječmen, T.; Tuzhilkin, R.; Šulc, M.; Photo-Methionine, Azidohomoalanine and Homopropargylglycine Are Incorporated into Newly Synthesized Proteins at Different Rates and Differentially Affect the Growth and Protein Expression Levels of Auxotrophic and Prototrophic E. coli in Minimal Medium. International Journal of Molecular Sciences, 2023, Roč. 24, č. 14, IF=5.6 DOI: 10.3390/ijms241411779

Osičková, A.; Knoblochová, Š.; Bumba, L.; Man, P.; Kalaninová, Z.; Lepesheva, A.; Jurnečka, D.; Čížková, M.; Biedermannová, L.; Goldsmith, JA.; Maynard, JA.; McLellan, JS.; Osička, R.; Šebo, P.; Mašín, J.; A conserved tryptophan in the acylated segment of RTX toxins controls their β₂ integrin–independent cell penetration. Journal of Biological Chemistry, 2023, Roč. 299, č. 8, IF=4.8 DOI: 10.1016/j.jbc.2023.104978

Zákopčaník, M.; Kavan, D.; Novák, P.; Loginov, DS.; Quantifying the Impact of the Peptide Identification Framework on the Results of Fast Photochemical Oxidation of Protein Analysis. Journal of Proteome Research, 2023, Roč. 23, č. 2, s.609-617. IF=4.4 DOI: 10.1021/acs.jproteome.3c00390

Vávra, J.; Sergunin, A.; Farná, A.; Ovad, T.; Shimizu, T.; Martínková, M.; Is ATP the Only Nucleoside Triphosphate among ATP, CTP, GTP, and UTP to Have a Role in Kinase Catalysis of Heme-Regulated Inhibitor toward eIF2α during Lung Cancer Development?. Catalysts, 2023, Roč. 13, č. 2, IF=3.9 DOI: 10.3390/catal13020281

Dvořák, J.; Nováková, J.; Kraftová, L.; Heringová, V.; Matějovič, M.; Raděj, J.; Karvunidis, T.; Horák, J.; Královcová, M.; Hrabák, J.; Kalaninová, Z.; Volný, M.; Novák, P.; Pompach, P.; The rapid detection of procalcitonin in septic serum using immunoaffinity MALDI chips. Clinical Proteomics, 2023, Roč. 20, č. 1, IF=3.8 DOI: 10.1186/s12014-023-09410-3

Di Carluccio, C.; Milanesi, F.; Civera, M.; de Sousa Santos Abreu, C.; Sattin, S.; Francesconi, O.; Molinaro, A.; Vaněk, O.; Marchetti, R.; Silipo, A.; Tumor Carbohydrate Associated Antigen Analogs as Potential Binders for Siglec-7. European Journal of Organic Chemistry, 2023, Roč. 26, č. 40, IF=2.8 DOI: 10.1002/ejoc.202300644

2022 (z celkového počtu 35)

Bláha, J.; Skálová, T.; Kalousková, B.; Skořepa, O.; Cmunt, D.; Grobárová, V.; Pažický, S.; Poláchová, E.; de Sousa Santos Abreu, C.; Stránský, J.; Kovaľ, T.; Dušková, J.; Zhao, Y.; Harlos, K.; Hašek, J.; Dohnálek, J.; Vaněk, O.; Structure of the human NK cell NKR-P1:LLT1 receptor:ligand complex reveals clustering in the immune synapse. Nature Communications [online], 2022, Roč. 13, č. 1, IF=17.694 DOI: 10.1038/s41467-022-32577-6

Poryvai, A.; Galkin, M.; Shvadchak, V.; Slanina, T.; Red-Shifted Water-Soluble BODIPY Photocages for Visualisation and Controllable Cellular Delivery of Signaling Lipids. Angewandte Chemie - International Edition, 2022, Roč. 61, č. 34, s.nestránkováno. IF=16.823 DOI: 10.1002/anie.202205855

Majerová, T.; Konvalinka, J.; Viral proteases as therapeutic targets. Molecular Aspects of Medicine, 2022, Roč. 88, č. December 2022, s.nestránkováno. IF=16.337 DOI: 10.1016/j.mam.2022.101159

Radilová, K.; Zima, V.; Kráľ, M.; Machara, A.; Majer, P.; Hodek, J.; Weber, J.; Brynda, J.; Strmeň, T.; Konvalinka, J.; Kožíšek, M.; Thermodynamic and structural characterization of an optimized peptide-based inhibitor of the influenza polymerase PA-PB1 subunit interaction. Antiviral Research, 2022, Roč. 208, č. December, IF=10.103 DOI: 10.1016/j.antiviral.2022.105449

Giacobelli, VG.; Fujishima, K.; Lepšík, M.; Tretyachenko, V.; Kadavá, T.; Makarov, M.; Bednárová, L.; Novák, P.; Hlouchová, K.; In Vitro Evolution Reveals Noncationic Protein-RNA Interaction Mediated by Metal Ions. Molecular Biology and Evolution, 2022, Roč. 39, č. 3, s.nestránkováno. IF=8.800 DOI: 10.1093/molbev/msac032

Vavřina, Z.; Perlíková, P.; Milisavljević, N.; Chevrier, F.; Smola, M.; Smith, J.; Dejmek, M.; Havlíček, V.; Buděšínský, M.; Liboska, R.; Vaneková, L.; Brynda, J.; Bouřa, E.; Řezáčová, P.; Hocek, M.; Birkuš, G.; Design, Synthesis, and Biochemical and Biological Evaluation of Novel 7-Deazapurine Cyclic Dinucleotide Analogues as STING Receptor Agonists. Journal of Medicinal Chemistry, 2022, Roč. 65, č. 20, s.14082-14103. IF=8.039 DOI: 10.1021/acs.jmedchem.2c01305

Polák, M.; Yassaghi, G.; Kavan, D.; Filandr, F.; Fiala, J.; Kukačka, Z.; Halada, P.; Loginov, DS.; Novák, P.; Utilization of Fast Photochemical Oxidation of Proteins and Both Bottom-up and Top-down Mass Spectrometry for Structural Characterization of a Transcription Factor–dsDNA Complex. Analytical Chemistry, 2022, Roč. 94, č. 7, s.3203-3210. IF=8.008 DOI: 10.1021/acs.analchem.1c04746

Yassaghi, G.; Kukačka, Z.; Fiala, J.; Kavan, D.; Halada, P.; Volný, M.; Novák, P.; Top-Down Detection of Oxidative Protein Footprinting by Collision-Induced Dissociation, Electron-Transfer Dissociation, and Electron-Capture Dissociation. Analytical Chemistry, 2022, Roč. 94, č. 28, s.9993-10002. IF=8.008 DOI: 10.1021/acs.analchem.1c05476

Vavrová, K.; Indra, R.; Pompach, P.; Heger, Z.; Hodek, P.; The impact of individual human cytochrome P450 enzymes on oxidative metabolism of anticancer drug lenvatinib. Biomedicine & Pharmacotherapy, 2022, Roč. 145, č. January, s.nestránkováno. IF=7.419 DOI: 10.1016/j.biopha.2021.112391

Golshani, M.; Rahman, WU.; Osičková, A.; Holubová, J.; Lora, J.; Balashova, N.; Šebo, P.; Osička, R.; Filamentous Hemagglutinin of Bordetella pertussis Does Not Interact with the β₂ Integrin CD11b/CD18. International Journal of Molecular Sciences [online], 2022, Roč. 23, č. 20, s.nestránkováno. IF=6.208 DOI: 10.3390/ijms232012598

Bělonožníková, K.; Hýsková, V.; Chmelík, J.; Kavan, D.; Čeřovská, N.; Ryšlavá, H.; Pythium oligandrum in plant protection and growth promotion: Secretion of hydrolytic enzymes, elicitors and tryptamine as auxin precursor. Microbiological Research, 2022, Roč. 258, č. May, IF=5.070 DOI: 10.1016/j.micres.2022.126976

Kozlík, P.; Molnárová, K.; Ječmen, T.; Křížek, T.; Bosáková, Z.; Prediction of Intact N-Glycopeptide Retention Time Windows in Hydrophilic Interaction Liquid Chromatography. Molecules, 2022, Roč. 27, č. 12, s.nestránkováno. IF=4.927 DOI: 10.3390/molecules27123723

Vávra, J.; Sergunin, A.; Jeřábek, P.; Shimizu, T.; Martínková, M.; Signal transduction mechanisms in heme-based globin-coupled oxygen sensors with a focus on a histidine kinase (AfGcHK) and a diguanylate cyclase (YddV or EcDosC). Biological Chemistry, 2022, Roč. 403, č. 11-12, s.1031-1042. IF=4.700 DOI: 10.1515/hsz-2022-0185

2021 (z celkového počtu 48)

Fojtík , L.; Fiala, J.; Pompach, P.; Chmelík, J.; Matoušek, V.; Beier, P.; Kukačka, Z.; Novák, P.; Fast Fluoroalkylation of Proteins Uncovers the Structure and Dynamics of Biological Macromolecules. Journal of the American Chemical Society, 2021, Roč. 143, č. 49, s.20670-20679. IF=15.419 DOI: 10.1021/jacs.1c07771

Felice, AKG.; Schuster, Ch.; Kádek, A.; Filandr, F.; Laurent, ChVFP.; Scheiblbrandner, S.; Schwaiger, L.; Schachinger, F.; Kracher, D.; Sygmund, Ch.; Man, P.; Halada, P.; Oostenbrink, Ch.; Ludwig, R.; Chimeric Cellobiose Dehydrogenases Reveal the Function of Cytochrome Domain Mobility for the Electron Transfer to Lytic Polysaccharide Monooxygenase. ACS Catalysis, 2021, Roč. 11, č. 2, s.517-532. IF=13.084 DOI: 10.1021/acscatal.0c05294

Luis Pacheco-Garcia, J.; Anoz-Carbonell, E.; Vaňková, P.; Kannan, A.; Palomino-Morales, R.; Mesa-Torres, N.; Salido, E.; Man, P.; Medina, M.; Naganathan, AN.; Pey, AL.; Structural basis of the pleiotropic and specific phenotypic consequences of missense mutations in the multifunctional NAD(P)H:quinone oxidoreductase 1 and their pharmacological rescue. Redox Biology [online], 2021, Roč. 46, č. October 2021, s.nestránkováno. IF=11.799 DOI: 10.1016/j.redox.2021.102112

Stehlík, Š.; Henych, J.; Štenclová, P.; Král, R.; Zemenová, P.; Pangrác, J.; Vaněk, O.; Kromka, A.; Rezek, B.; Size and nitrogen inhomogeneity in detonation and laser synthesized primary nanodiamond particles revealed via salt-assisted deaggregation. Carbon, 2021, Roč. 171, č. January, s.230-239. IF=9.594 DOI: 10.1016/j.carbon.2020.09.026

Cechová, K.; Lan, Ch.; Macik, M.; Barthes, NPF.; Jung, M.; Ulbrich, MH.; Kappa but not delta or mu opioid receptors form homodimers at low membrane densities. Cellular and Molecular Life Sciences, 2021, Roč. 78, č. 23, s.7557-7568. IF=9.261 DOI: 10.1007/s00018-021-03963-y

Kryštůfek, R.; Šácha, P.; Starková, J.; Brynda, J.; Hradilek, M.; Tloušt’ová, E.; Grzymska, J.; Rut, W.; Boucher, MJ.; Drąg, M.; Majer, P.; Hájek, M.; Řezáčová, P.; Madhani, HD.; Craik, ChS.; Konvalinka, J.; Re-emerging Aspartic Protease Targets: Examining Cryptococcus neoformans Major Aspartyl Peptidase 1 as a Target for Antifungal Drug Discovery. Journal of Medicinal Chemistry, 2021, Roč. 64, č. 10, s.6706-6719. IF=7.446 DOI: 10.1021/acs.jmedchem.0c02177

Priss, A.; Afitska, K.; Galkin, M.; Yushchenko, DA.; Shvadchak, VV.; Rationally Designed Protein-Based Inhibitor of alpha-Synuclein Fibrillization in Cells. Journal of Medicinal Chemistry, 2021, Roč. 64, č. 10, s.6827-6837. IF=7.446 DOI: 10.1021/acs.jmedchem.1c00086

Jakl, M.; Ćavar Zeljković, S.; Kovač, I.; Bělonožníková, K.; Jaklová Dytrtová, J.; Side effects of triazoles on treated crops. Chemosphere, 2021, Roč. 277, č. neuvedeno, s.1-10. IF=7.086 DOI: 10.1016/j.chemosphere.2021.130242

Kalousková, B.; Skořepa, O.; Cmunt, D.; de Sousa Santos Abreu, C.; Krejčová, K.; Bláha, J.; Sieglová, I.; Král, V.; Fábry, M.; Pola, R.; Pechar, M.; Vaněk, O.; Tumor Marker B7-H6 Bound to the Coiled Coil Peptide-Polymer Conjugate Enables Targeted Therapy by Activating Human Natural Killer Cells. Biomedicines [online], 2021, Roč. 9, č. 11, s.nestránkováno. IF=6.081 DOI: 10.3390/biomedicines9111597

Jáklová, K.; Feglarová, T.; Rex, S.; Heger, Z.; Eckschlager, T.; Hraběta, J.; Hodek, P.; Kolárik, M.; Indra, R.; Apoferritin/vandetanib association is long-term stable but does not improve pharmacological properties of vandetanib. International Journal of Molecular Sciences, 2021, Roč. 22, č. 8, s.nestránkováno. IF=5.924 DOI: 10.3390/ijms22084250

Dračínská, H.; Indra, R.; Jelínková, S.; Černá, V.; Arlt, VM.; Stiborová, M.; Benzo[a]pyrene-Induced Genotoxicity in Rats Is Affected by Co-Exposure to Sudan I by Altering the Expression of Biotransformation Enzymes. International Journal of Molecular Sciences, 2021, Roč. 22, č. 15, s.nestránkováno. IF=5.924 DOI: 10.3390/ijms22158062

Bárta, F.; Dedíková, A.; Bebová, M.; Dušková, Š.; Mráz, J.; Schmeiser, HH.; Arlt, VM.; Hodek, P.; Stiborová, M.; Co-Exposure to Aristolochic Acids I and II Increases DNA Adduct Formation Responsible for Aristolochic Acid I-Mediated Carcinogenicity in Rats. International Journal of Molecular Sciences [online], 2021, Roč. 22, č. 19, s.nestránkováno. IF=5.924 DOI: 10.3390/ijms221910479

Burská, D.; Stibůrek, L.; Křížová, J.; Vanišová, M.; Martínek, V.; Sládková, J.; Zámečník, J.; Honzík, T.; Zeman, J.; Hansíková, H.; Tesařová, M.; Homozygous missense mutation in UQCRC2 associated with severe encephalomyopathy, mitochondrial complex III assembly defect and activation of mitochondrial protein quality control. Biochimica et Biophysica Acta - Molecular Basis of Disease, 2021, Roč. 1867, č. 8, s.nestránkováno. IF=5.187 DOI: 10.1016/j.bbadis.2021.166147

Dostál, J.; Brynda, J.; Vaňková, L.; Zia, SR.; Pichová, I.; Heidingsfeld, O.; Lepšík, M.; Structural determinants for subnanomolar inhibition of the secreted aspartic protease Sapp1p from Candida parapsilosis. Journal of Enzyme Inhibition and Medicinal Chemistry, 2021, Roč. 36, č. 1, s.914-921. IF=5.051 DOI: 10.1080/14756366.2021.1906664

Filandrová, R.; Vališ, K.; Černý, J.; Chmelík, J.; Slavata, L.; Fiala, J.; Rosůlek, M.; Kavan, D.; Man, P.; Chum, T.; Cebecauer, M.; Fabris, D.; Novák, P.; Motif orientation matters: Structural characterization of TEAD1 recognition of genomic DNA. Structure, 2021, Roč. 29, č. 4, s.345-356.e8. IF=5.006 DOI: 10.1016/j.str.2020.11.018

Hýsková, V.; Bělonožníková, K.; Šmeringaiová, I.; Kavan, D.; Ingr, M.; Ryšlavá, H.; How is the activity of shikimate dehydrogenase from the root of Petroselinum crispum (parsley) regulated and which side reactions are catalyzed?. Phytochemistry, 2021, Roč. 190, č. October 2021, s.nestránkováno. IF=4.072 DOI: 10.1016/j.phytochem.2021.112881

2020 (z celkového počtu 50)

Dostál, J.; Blaha, J; Hadravová, R.; Hubálek, M.; Heidingsfeld, O.; Pichová, I.: Cellular Localization of Carbonic Anhydrase Nce103p in Candida albicans and Candida parapsilosis. International Journal of Molecular Sciences [online]. 2020, roč. 21, č. 3, s. nestránkováno. IF=4.556 DOI: 10.3390/ijms21030850

Skálová, T.; Lengálová, A.; Dohnálek, J.; Harlos, K.; Mihalčin, P.; Kolenko, P.; Stráňava, M.; Bláha, J.; Shimizu, T.; Martínková, M.: Disruption of the dimerization interface of the sensing domain in the dimeric heme-based oxygen sensor AfGcHK abolishes bacterial signal transduction. Journal of Biological Chemistry. 2020, roč. 295, č. 6, s. 1587-1597. IF=4.238 DOI: 10.1074/jbc.RA119.011574

Stoszko, M.; Al-Hatmi, A. M. S.; Skriba, A.; Roling, M.; Ne, E.; Crespo, R.; Mueller, Y. M.; Najafzadeh, M. J.; Kang, J.; Ptáčková, R.; Lemasters, E.; Biswas, P.; Bertoldi, A.; Kan, T. W.; De Crignis, E.; Šulc, M.; Lebbink, L.; Rokx, C.; Verbon, A.; Van Ijcken, W.; Katsikis, P. D.; Palstra, R. J.; Havlíček, V.; De Hoog, S.; Mahmoudi, T.: Gliotoxin, identified from a screen of fungal metabolites, disrupts 7SK snRNP, releases P-TEFb, and reverses HIV-1 latency. Science advances [online]. 2020, roč. 6, č. 33, s. nestránkováno. IF=13.117 DOI: 10.1126/sciadv.aba6617

Indra, R.; Vavrová, K.; Pompach, P.; Heger, Z.; Hodek, P.: Identification of Enzymes Oxidizing the Tyrosine Kinase Inhibitor Cabozantinib: Cabozantinib Is Predominantly Oxidized by CYP3A4 and Its Oxidation Is Stimulated by cyt b(5) Activity. Biomedicines [online]. 2020, roč. 8, č. 12, s. nestránkováno. IF=4.717 DOI: 10.3390/biomedicines8120547

Dedíková, A.; Bárta, F.; Martínek, V.; Kotalík, K.; Dušková, Š.; Mráz, J.; Arlt, V. M.; Stiborová, M.; Hodek, P.: In vivo metabolism of aristolochic acid I and II in rats is influenced by their co-exposure. Chemical Research in Toxicology. 2020, roč. 33, č. 11, s. 2804-2818. IF=3.184 DOI: 10.1021/acs.chemrestox.0c00198

Fiala, J.; Kukačka, Z.; Novák, P.: Influence of cross-linker polarity on selectivity towards lysine side chains. Journal of Proteomics. 2020, roč. 218, č. April, s. nestránkováno. IF=3.509 DOI: 10.1016/j.jprot.2020.103716

Smidova, V.; Michalek, P.; Goliasova, Z.; Eckschlager, T.; Hodek, P.; Adam, V.; Heger, Z.: Nanomedicine of tyrosine kinase inhibitors. Theranostics. 2021, roč. 11, č. 4, s. 1546-1567. IF=8.579 DOI: 10.7150/thno.48662

Skořepa, O.; Pažický, S.; Kalousková, B.; Bláha, J.; De Sousa Santos Abreu, C.; Ječmen, T.; Rosůlek, M.; Fish, A.; Sedivy, A.; Harlos, K.; Dohnálek, J.; Skálová, T.; Vaněk, O.: Natural Killer Cell Activation Receptor NKp30 Oligomerization Depends on ItsN-Glycosylation. Cancers. 2020, roč. 12, č. 7, s. nestránkováno. IF=6.126 DOI: 10.3390/cancers12071998

Bělonožníková, K.; Vaverová, K.; Vaněk, T.; Kolařík, M.; Hýsková, V.; Vaňková, R.; Dobrev, P. I.; Křížek, T.; Hodek, O.; Čokrtová, K.; Štípek, A.; Ryšlavá, H.: Novel Insights into the Effect of Pythium Strains on Rapeseed Metabolism. Microorganisms. 2020, roč. 8, č. 10, s. nestránkováno. IF=4.152 DOI: 10.3390/microorganisms8101472

Sumová, P.; Polanská, N.; Leštinová, T.; Spitzová, T.; Kalousková, B.; Vaněk, O.; Volf, P.; Rohoušová, I.: Phlebotomus perniciosus Recombinant Salivary Proteins Polarize Murine Macrophages Toward the Anti-Inflammatory Phenotype. Frontiers in Cellular and Infection Microbiology. 2020, roč. 10, č. August 2020, s. nestránkováno. IF=4.123 DOI: 10.3389/fcimb.2020.00427

Mašín, J.; Osičková, A.; Jurnečka, D.; Klímová, N.; Khaliq, H.; Šebo, P.; Osička, R.: Retargeting from the CR3 to the LFA-1 receptor uncovers the adenylyl cyclase enzyme-translocating segment of Bordetella adenylate cyclase toxin. Journal of Biological Chemistry. 2020, roč. 295, č. 28, s. 9349-9365. IF=4.238 DOI: 10.1074/jbc.RA120.013630

Dzianová, P.; Asai, S.; Chrudinová, M.; Kosinová, L.; Potalitsyn, P.; Šácha, P.; Hadravová, R.; Selicharová, I.; Kříž, J.; Turkenburg, J. P.; Brzozowski, A. M.; Jiráček, J.; Žáková, L.: The efficiency of insulin production and its content in insulin-expressing model beta-cells correlate with their Zn(2+) levels. Open Biology. 2020, roč. 10, č. 10, s. nestránkováno. IF=4.931 DOI: 10.1098/rsob.200137

Trčka, F.; Ďurech, M.; Vaňková, P.; Vandová, V.; Šimončík, O.; Kavan, D.; Vojtěšek, B.; Müller, P.; Man, P.: The interaction of the mitochondrial protein importer TOMM34 with HSP70 is regulated by TOMM34 phosphorylation and binding to 14-3-3 adaptors. Journal of Biological Chemistry. 2020, roč. 295, č. 27, s. 8928-8944. IF=4.238 DOI: 10.1074/jbc.RA120.012624

Jaklová Dytrtová, J.; Bělonožníková, K.; Jakl, M.; Ryšlavá, H.: Triazoles and aromatase: The impact of copper cocktails. Environmental Pollution. 2020, roč. 266, č. November 2020 (Part 1), s. nestránkováno. IF=6.793 DOI: 10.1016/j.envpol.2020.115201

Zima, V.; Radilová, K.; Kožíšek, M.; Albinana, C. B.; Karlukova, E.; Brynda, J.; Fanfrlík, J.; Flieger, M.; Hodek, J.; Weber, J.; Majer, P.; Konvalinka, J.; Machara, A.: Unraveling the anti-influenza effect of flavonoids: Experimental validation of luteolin and its congeners as potent influenza endonuclease inhibitors. European Journal of Medicinal Chemistry. 2020, roč. 208, č. December, s. nestránkováno. IF=5.573 DOI: 10.1016/j.ejmech.2020.112754

Kalábová, D.; Filandr, F.; Alblová, M.; Petrvalská, O.; Horváth, M.; Man, P.; Obšil, T.; Obšilová, V.: 14-3-3 protein binding blocks the dimerization interface of caspase-2. FEBS Journal. 2020, roč. 287, č. 16, s. 3494-3510. IF=4.392 DOI: 10.1111/febs.15215

2019 (z celkového počtu 41)

Vorlová, B.; Sedlák, F.; Kašpárek, P.; Šrámková, K.; Malý, M.; Zámečník, J.; Šácha, P.; Konvalinka, J.; A novel PSMA/GCPII-deficient mouse model shows enlarged seminal vesicles upon aging. Prostate, 2019, Roč. 79, č. 2, s.126-139. IF=2.876 DOI: 10.1002/pros.23717

Indra, R.; Černá, T.; Heger, Z.; Hraběta, J.; Wilhelm, M.; Dostalova, S.; Lengálová, A.; Martínková, M.; Adam, V.; Eckschlager, T.; Schmeiser, HH.; Arlt, VM.; Stiborová, M.; Ellipticine-loaded apoferritin nanocarrier retains DNA adduct-based cytochrome P450-facilitated toxicity in neuroblastoma cells. Toxicology, 2019, Roč. 419, č. May, s.40-54. IF=3.547 DOI: 10.1016/j.tox.2019.03.009

Trčka, F.; Ďurech, M.; Vaňková, P.; Chmelík, J.; Martinková, V.; Hausner, J.; Kádek, A.; Marcoux, J.; Klumpler, T.; Vojtěšek, B.; Müller, P.; Man, P.; Human Stress-inducible Hsp70 Has a High Propensity to Form ATP-dependent Antiparallel Dimers That Are Differentially Regulated by Cochaperone Binding. Molecular and Cellular Proteomics, 2019, Roč. 18, č. 2, s.320-337. IF=4.828 DOI: 10.1074/mcp.RA118.001044

Indra, R.; Pompach, P.; Martínek, V.; Takácsová, P.; Vavrová, K.; Heger, Z.; Adam, V.; Eckschlager, T.; Kopečková, K.; Arlt, VM.; Stiborová, M.; Identification of Human Enzymes Oxidizing the Anti-Thyroid-Cancer Drug Vandetanib and Explanation of the High Efficiency of Cytochrome P450 3A4 in its Oxidation. International Journal of Molecular Sciences, 2019, Roč. 20, č. 14, s.nestránkováno. IF=4.183 DOI: 10.3390/ijms20143392

Le, ST.; Malinovská, L.; Vašková, M.; Mező, E.; Kelemen, V.; Borbás, A.; Hodek, P.; Wimmerová, M.; Csávás, M.; Investigation of the Binding Affinity of a Broad Array of l-Fucosides with Six Fucose-Specific Lectins of Bacterial and Fungal Origin. Molecules, 2019, Roč. 24, č. 12, s.nestránkováno. IF=3.060 DOI: 10.3390/molecules24122262

Reed, L.; Indra, R.; Mrízová, I.; Moserová, M.; Schmeiser, HH.; Wolf, ChR.; Henderson, CJ.; Stiborová, M.; Phillips, DH.; Arlt, VM.; Application of hepatic cytochrome b(5)/P450 reductase null (HBRN) mice to study the role of cytochrome b(5) in the cytochrome P450-mediated bioactivation of the anticancer drug ellipticine. Toxicology and Applied Pharmacology, 2019, Roč. 366, č. 1 March 2019, s.64-74. IF=3.585 DOI: 10.1016/j.taap.2019.01.020

Hernychová, L.; Rosůlek, M.; Kádek, A.; Mareška, V.; Chmelík, J.; Adámková, L.; Grobárová, V.; Šebesta, O.; Kukačka, Z.; Skála, K.; Spiwok, V.; Černý, J.; Novák, P.; The C-type lectin-like receptor Nkrp1b: Structural proteomics reveals features affecting protein conformation and interactions. Journal of Proteomics, 2019, Roč. 196, č. March 2019, s.162-172. IF=3.537 DOI: 10.1016/j.jprot.2018.11.007

Staněk, O.; Mašín, J.; Osička, R.; Jurnečka, D.; Osičková, A.; Šebo, P.; Rapid Purification of Endotoxin-Free RTX Toxins. Toxins, 2019, Roč. 11, č. 6, s.nestránkováno. IF=3.895 DOI: 10.3390/toxins11060336

Lengálová, A.; Fojtíková-Prošková, V.; Vávra, J.; Martínek, V.; Stráňava, M.; Shimizu, T.; Martínková, M.; Kinetic analysis of a globin-coupled diguanylate cyclase, YddV: Effects of heme iron redox state, axial ligands, and heme distal mutations on catalysis. Journal of Inorganic Biochemistry, 2019, Roč. 201, č. December, s.nestránkováno. IF=3.224 DOI: 10.1016/j.jinorgbio.2019.110833

Shimizu, T.; Lengálová, A.; Martínek, V.; Martínková, M.; Heme: Emergent roles of heme in signal transduction, functional regulation and as catalytic centres. Chemical Society Reviews, 2019, Roč. 48, č. 24, s.5624-5657. IF=40.443 DOI: 10.1039/c9cs00268e

Vaněk, O.; Celadová, P.; Skořepa, O.; Bláha, J.; Kalousková, B.; Dvorská, A.; Poláchová, E.; Pucholtová, H.; Kavan, D.; Pompach, P.; Hofbauerová, K.; Kopecký, V.; Mesci, A.; Voigt, S.; Carlyle, JR.; Production of recombinant soluble dimeric C-type lectin-like receptors of rat natural killer cells. Scientific Reports, 2019, Roč. 9, č. November, s.nestránkováno. IF=4.011 DOI: 10.1038/s41598-019-52114-8

Malinovská, L.; Le, ST.; Herczeg, M.; Vašková, M.; Houser, J.; Fujdiarová, E.; Komárek, J.; Hodek, P.; Borbás, A.; Wimmerová, M.; Csávás, M.; Synthesis of beta-d-galactopyranoside-Presenting Glycoclusters, Investigation of Their Interactions with Pseudomonas aeruginosa Lectin A (PA-IL) and Evaluation of Their Anti-Adhesion Potential. Biomolecules, 2019, Roč. 9, č. 11, s.nestránkováno. IF=4.694 DOI: 10.3390/biom9110686

Sborchia, M.; De Prez, EG.; Antoine, M.; Bienfait, L.; Indra, R.; Valbuena, G.; Phillips, DH.; Nortier, JL.; Stiborová, M.; Keun, HCh.; Arlt, VM.; The impact of p53 on aristolochic acid I-induced nephrotoxicity and DNA damage in vivo and in vitro. Archives of Toxicology, 2019, Roč. 93, č. 11, s.3345-3366. IF=5.741 DOI: 10.1007/s00204-019-02578-4

Slavata, L.; Chmelík, J.; Kavan, D.; Filandrová, R.; Fiala, J.; Rosůlek, M.; Mrázek, H.; Kukačka, Z.; Vališ, K.; Man, P.; Miller, M.; McIntyre, W.; Fabris, D.; Novák, P.; MS-Based Approaches Enable the Structural Characterization of Transcription Factor/DNA Response Element Complex. Biomolecules, 2019, Roč. 9, č. 10, s.nestránkováno. IF=4.694 DOI: 10.3390/biom9100535

Möller, IR.; Slivacka, M.; Hausner, J.; Nielsen, AK.; Pospíšilová, E.; Merkle, PS.; Lišková, R.; Polák, M.; Loland, CJ.; Kádek, A.; Man, P.; Rand, KD.; Improving the Sequence Coverage of Integral Membrane Proteins during Hydrogen/Deuterium Exchange Mass Spectrometry Experiments. Analytical Chemistry, 2019, Roč. 91, č. 17, s.10970-10978. IF=6.350 DOI: 10.1021/acs.analchem.9b00973

Willen, LAA.; Leštinová, T.; Kalousková, B.; Sumová, P.; Spitzová, T.; Velez, R.; Domenech, E.; Vaněk, O.; Gállego, M.; Mertens, P.; Volf, P.; Field study of the improved rapid sand fly exposure test in areas endemic for canine leishmaniasis. PLoS Neglected Tropical Diseases [online], 2019, Roč. 13, č. 11, s.nestránkováno. IF=4.487 DOI: 10.1371/journal.pntd.0007832

PATENTY

Macromolecular conjugates for visualization and separation of proteins and cells. Původce: Šácha, Pavel - Konvalinka, Jan - Schimer, Jiří - Knedlík, Tomáš - Navrátil, Václav - Tykvart, Jan - Sedlák, František - Majer, Pavel - Cígler, Petr - Šubr, Vladimír - Ulbrich, Karel - Strohalm, Jiří. Patent přijatý v zemích: Evropa, Kanada, Singapur, Izrael, Austrálie, USA.

2018 (z celkového počtu 46)

Shvadchak, VV.; Afitska, K.; Yushchenko, DA.; Inhibition of α-Synuclein Amyloid Fibril Elongation by Blocking Fibril Ends. Angewandte Chemie - International Edition, 2018, Roč. 57, č. 20, s.5690-5694. IF=12.102 DOI: 10.1002/anie.201801071

Darebná, P.; Špička, J.; Kučera, R.; Topolčan, O.; Navrátilová, E.; Růžička, V.; Volný, M.; Novák, P.; Pompach, P.; Detection and Quantification of Carbohydrate-Deficient Transferrin by MALDI-Compatible Protein Chips Prepared by Ambient Ion Soft Landing. Clinical Chemistry, 2018, Roč. 64, č. 9, s.1319-1326. IF=8.636 DOI: 10.1373/clinchem.2017.285452

Rozbeský, D.; Rosůlek, M.; Kukačka, Z.; Chmelík, J.; Man, P.; Novák, P.; Impact of Chemical Cross-Linking on Protein Structure and Function. Analytical Chemistry, 2018, Roč. 90, č. 2, s.1104-1113. IF=6.042 DOI: 10.1021/acs.analchem.7b02863

Osičková, A.; Balashova, N.; Mašín, J.; Šulc, M.; Röderová, J.; Wald, T.; Brow, A.; Koufos, E.; Chang, E.; Giannakakis, A.; Lally, E.; Osička, R.; Cytotoxic activity of Kingella kingae RtxA toxin depends on post-translational acylation of lysine residues and cholesterol binding. Emerging Microbes and Infections, 2018, Roč. 7, č. 1 (listopad 2018), s.nestránkováno. IF=6.032 DOI: 10.1038/s41426-018-0179-x

Reed, L.; Mrízová, I.; Bárta, F.; Indra, R.; Moserová, M.; Kopka, K.; Schmeiser, HH.; Wolf, CR.; Henderson, CJ.; Stiborová, M.; Phillips, DH.; Arlt, VM.; Cytochrome b(5) impacts on cytochrome P450-mediated metabolism of benzo[a]pyrene and its DNA adduct formation: studies in hepatic cytochrome b(5)/P450 reductase null (HBRN) mice. Archives of Toxicology, 2018, Roč. 92, č. 4, s.1625-1638. IF=5.728 DOI: 10.1007/s00204-018-2162-7

Chaloupková, Z.; Balzerová, A.; Bařinková, J.; Medříková, Z.; Šácha, P.; Beneš, P.; Ranc, V.; Konvalinka, J.; Zbořil, R.; Label-free determination of prostate specific membrane antigen in human whole blood at nanomolar levels by magnetically assisted surface enhanced Raman spectroscopy. Analytica Chimica Acta, 2018, Roč. 997, č. 2 January 2018, s.44-51. IF=5.123 DOI: 10.1016/j.aca.2017.10.008

Jaklová Dytrtová, J.; Straka, M.; Bělonožníková, K.; Jakl, M.; Ryšlavá, H.; Does resveratrol retain its antioxidative properties in wine? Redox behaviour of resveratrol in the presence of Cu(II) and tebuconazole. Food Chemistry, 2018, Roč. 262, č. October 2018, s.221-225. IF=4.946 DOI: 10.1016/j.foodchem.2018.04.096

Neburková, J.; Sedlák, F.; Žáčková Suchanová, J.; Kostka, L.; Šácha, P.; Šubr, V.; Etrych, T.; Šimon, P.; Bařinková, J.; Kryštůfek, R.; Španielová, H.; Forstová, J.; Konvalinka, J.; Cígler, P.; Inhibitor-GCPII Interaction: Selective and Robust System for Targeting Cancer Cells with Structurally Diverse Nanoparticles. Molecular Pharmaceutics, 2018, Roč. 15, č. 8, s.2932-2945. IF=4.556 DOI: 10.1021/acs.molpharmaceut.7b00889

Škerlová, J.; Bláha, J.; Pachl, P.; Hofbauerová, K.; Kukačka, Z.; Man, P.; Pompach, P.; Novák, P.; Otwinowski, Z.; Brynda, J.; Vaněk, O.; Řezáčová, P.; Crystal structure of native beta-N-acetylhexosaminidase isolated from Aspergillus oryzae sheds light onto its substrate specificity, high stability, and regulation by propeptide. FEBS Journal, 2018, Roč. 285, č. 3, s.580-598. IF=4.530 DOI: 10.1111/febs.14360

Humpolíčková, J.; Weber, J.; Starková, J.; Mašínová, E.; Gunterová, J.; Flaisigová, I.; Konvalinka, J.; Majerová, T.; Inhibition of the precursor and mature forms of HIV-1 protease as a tool for drug evaluation. Scientific Reports, 2018, Roč. 8, č. July 2018, s.nestránkováno. IF=4.122 DOI: 10.1038/s41598-018-28638-w

Chrudinová, M.; Žáková, L.; Marek, Socha, O.; Buděšínský, M.; Hubálek, Pícha, J.; Macháčková, K.; Jiráček, J.; Selicharová, I.; A versatile insulin analog with high potency for both insulin and insulin-like growth factor 1 receptors: Structural implications for receptor binding. Journal of Biological Chemistry, 2018, Roč. 293, č. 43, s.16818-16829. IF=4.011 DOI: 10.1074/jbc.RA118.004852

Zahradník, J.; Nunvář, J.; Pařízková, H.; Kolářová, L.; Palyzová, A.; Marešová, H.; Grulich, M.; Kyslíková, E.; Kyslík, P.; Agrobacterium bohemicum sp. nov. isolated from poppy seed wastes in central Bohemia. Systematic and Applied Microbiology, 2018, Roč. 41, č. 3, s.184-190. IF=3.899 DOI: 10.1016/j.syapm.2018.01.003

Baker, S.; Arlt, V.; Indra, R.; Joel, M.; Stiborová, M.; Eardley, I.; Ahmad, N.; Otto, W.; Burger, M.; Rubenwolf, P.; Phillips, D.; Southgate, J.; Differentiation-associated urothelial cytochrome P450 oxidoreductase predicates the xenobiotic-metabolizing activity of "luminal" muscle-invasive bladder cancers. Molecular Carcinogenesis, 2018, Roč. 57, č. 5, s.606-618. IF=3.851 DOI: 10.1002/mc.22784

Černá, T.; Hraběta, J.; Eckschlager, T.; Frei, E.; Schmeiser, H.; Arlt, V.; Stiborová, M.; The Histone Deacetylase Inhibitor Valproic Acid Exerts a Synergistic Cytotoxicity with the DNA-Damaging Drug Ellipticine in Neuroblastoma Cells. International Journal of Molecular Sciences, 2018, Roč. 19, č. 1, s.nestránkováno. IF=3.687 DOI: 10.3390/ijms19010164

Hodek, O.; Křížek, T.; Coufal, P.; Ryšlavá, H.; Online screening of alpha-amylase inhibitors by capillary electrophoresis. Analytical and Bioanalytical Chemistry, 2018, Roč. 410, č. 17, s.4213-4218. IF=3.307 DOI: 10.1007/s00216-018-1073-z

Stiborová, M.; Dračínská, H.; Bořek Dohalská, L.; Klusoňová, Z.; Holecová, J.; Martínková, M.; Schmeiser, HH.; Arlt, VM.; Exposure to endocrine disruptors 17alpha-ethinylestradiol and estradiol influences cytochrome P450 1A1-mediated genotoxicity of benzo[a]pyrene and expression of this enzyme in rats. Toxicology, 2018, Roč. 400-401, č. MAY 2018, s.48-56. IF=3.265 DOI: 10.1016/j.tox.2018.04.001

2017 (z celkového počtu 51)

Navrátil, V.; Schimer, J.; Tykvart, J.; Knedlík, T.; Vik, V.; Majer, P.; Konvalinka, J.; Šácha, P.; DNA-linked Inhibitor Antibody Assay (DIANA) for sensitive and selective enzyme detection and inhibitor screening. Nucleic Acids Research, 2017, Roč. 45, č. 2, s.nestránkováno. IF=10.162 DOI: 10.1093/nar/gkw853

Arlt, VM.; Meinl, W.; Florian, S.; Nagy, E.; Bárta, F.; Thomann, M.; Mrízová, I.; Krais, AM.; Liu, M.; Richards, M.; Mirza, A.; Kopka, K.; Phillips, DH.; Glatt, H.; Stiborová, M.; Schmeiser, HH.; Impact of genetic modulation of SULT1A enzymes on DNA adduct formation by aristolochic acids and 3-nitrobenzanthrone. Archives of Toxicology, 2017, Roč. 91, č. 4, s.1957-1975. IF=5.901 DOI: 10.1007/s00204-016-1808-6

Vališ, K.; Grobárová, V.; Hernychová, L.; Bugáňová, M.; Kavan, D.; Kalous, M.; Černý, J.; Stodůlková, E.; Kuzma, M.; Flieger, M.; Černý, J.; Novák, P.; Reprogramming of leukemic cell metabolism through the naphthoquinonic compound Quambalarine B. Oncotarget, 2017, Roč. 8, č. 61, s.103137-103153. IF=5.168 DOI: 10.18632/oncotarget.21663

Kádek, A.; Kavan, D.; Marcoux, J.; Stojko, J.; Felice, A.; Cianferani, S.; Ludwig, R.; Halada, P.; Man, P.; Interdomain electron transfer in cellobiose dehydrogenase is governed by surface electrostatics. Biochimica et Biophysica Acta - General Subjects, 2017, Roč. 1861, č. 2, s.157-167. IF=4.702 DOI: 10.1016/j.bbagen.2016.11.016

Treťjačenko, V.; Vymětal, J.; Bednarova, L.; Kopecký, V.; Hofbauerová, K.; Jindrová, H.; Hubalek, M.; Soucek, R.; Konvalinka, J.; Vondrasek, J.; Hlouchová, K.; Random protein sequences can form defined secondary structures and are well-tolerated in vivo. Scientific Reports, 2017, Roč. 7, č. 1, s.nestránkováno. IF=4.259 DOI: 10.1038/s41598-017-15635-8

Stráňava, M.; Man, P.; Skálová, T.; Kolenko, P.; Bláha, J.; Fojtíková, V.; Martínek, V.; Dohnálek, J.; Lengálová, A.; Rosůlek, M.; Shimizu, T.; Martínková, M.; Coordination and redox state-dependent structural changes of the heme-based oxygen sensor AfGcHK associated with intraprotein signal transduction. Journal of Biological Chemistry, 2017, Roč. 292, č. 51, s.20921-20935. IF=4.125 DOI: 10.1074/jbc.M117.817023

Škerlová, J.; Bláha, J.; Pachl, P.; Hofbauerová, K.; Kukačka, Z.; Man, P.; Pompach, P.; Novák, P.; Otwinowski, Z.; Brynda, J.; Vaněk, O.; Řezáčová, P.; Crystal structure of native β-N-acetylhexosaminidase isolated from Aspergillus oryzae sheds light onto its substrate specificity, high stability, and regulation by propeptide. FEBS Journal, 2018, Roč. 285, č. 3, s.580-598. IF=3.902 DOI: 10.1111/febs.14360

Hodek, O.; Křížek, T.; Coufal, P.; Ryšlavá, H.; Design of experiments for amino acid extraction from tobacco leaves and their subsequent determination by capillary zone electrophoresis. Analytical and Bioanalytical Chemistry, 2017, Roč. 409, č. 9, s.2383-2391. IF=3.431 DOI: 10.1007/s00216-017-0184-2

Stiborová, M.; Arlt, V.; Schmeiser, H.; DNA Adducts Formed by Aristolochic Acid Are Unique Biomarkers of Exposure and Explain the Initiation Phase of Upper Urothelial Cancer. International Journal of Molecular Sciences, 2017, Roč. 18, č. 10, s.nestránkováno. IF=3.226 DOI: 10.3390/ijms18102144

Mináriková, M.; Fojtíková, V.; Vyskočilová, E.; Sedláček, J.; Šikut, M.; Bořek Dohalská, L.; Stiborová, M.; Martínková, M.; The capacity and effectiveness of diosmectite and charcoal in trapping the compounds causing the most frequent intoxications in acute medicine: A comparative study. Environmental Toxicology and Pharmacology, 2017, Roč. 52, č. Jun 2017, s.214-220. IF=2.313 DOI: 10.1016/j.etap.2017.04.011

Tupec, M.; Hýsková, V.; Bělonožníková, K.; Hraníček, J.; Červený, V.; Ryšlavá, H.; Characterization of some potential medicinal plants from Central Europe by their antioxidant capacity and the presence of metal elements. Food Bioscience, 2017, Roč. 20, č. December 2017, s.43-50. IF=1.964 DOI: 10.1016/j.fbio.2017.08.001

Bláha, J.; Kalousková, B.; Skořepa, O.; Pažický, S.; Novák, P.; Vaněk, O.; High-level expression and purification of soluble form of human natural killer cell receptor NKR-P1 in HEK293S GnTI- cells. Protein Expression and Purification, 2017, Roč. 140, č. December 2017, s.36-43. IF=1.351 DOI: 10.1016/j.pep.2017.07.016

2016 (z celkového počtu 76)

Krais, AM.; Speksnijder, EN.; Melis, JPM.; Indra, R.; Moserová, M.; Godschalk, RW.; van Schooten, F.; Seidel, A.; Kopka, K.; Schmeiser, HH.; Stiborová, M.; Phillips, DH.; Luijten, M.; Arlt, VM.; The impact of p53 on DNA damage and metabolic activation of the environmental carcinogen benzo[a]pyrene: effects in Trp53(+/+), Trp53(+/-) and Trp53(-/-) mice. Archives of Toxicology, 2016, Roč. 90, č. 4, s.839-851. IF 5.98 DOI: 10.1007/s00204-015-1531-8

Jeřábek, P.; Florián, J.; Martínek, V.; Lipid molecules can induce an opening of membrane-facing tunnels in cytochrome P450 1A2. Physical Chemistry Chemical Physics, 2016, Roč. 18, č. 44, s.30344-30356. IF 4.44 DOI: 10.1039/c6cp03692a

Vašková, L.; Nosková, L.; Bláhová, B.; Wimmerová, M.; Dřevínek, P.; Kubíčková, B.; Stiborová, M.; Hodek, P.; Evaluation of anti-PAIIL lectin hen yolk antibody as an agent inhibiting Pseudomonas aeruginosa adherence to epithelial cells. Monatshefte für Chemie, 2016, Roč. 147, č. 5, s.889-896. IF 1.22 DOI: 10.1007/s00706-016-1687-9

Šulc, M.; Indra, R.; Moserová, M.; Schmeiser, H.; Frei, E.; Arlt, V.; Stiborová, M.; The impact of individual cytochrome P450 enzymes on oxidative metabolism of benzo[a]pyrene in human livers. Environmental and Molecular Mutagenesis, 2016, Roč. 57, č. 3, s.229-235. IF 2.63 DOI: 10.1002/em.22001

Jeřábek, P.; Florián, J.; Martínek, V.; Membrane-Anchored Cytochrome P450 1A2-Cytochrome b5 Complex Features an X-Shaped Contact between Antiparallel Transmembrane Helices. Chemical Research in Toxicology, 2016, Roč. 29, č. 4, s.626-636. IF 3.53 DOI: 10.1021/acs.chemrestox.5b00349

Dračínská, H.; Bárta, F.; Levová, K.; Hudecová, A.; Moserová, M.; Schmeiser, H.; Kopka, K.; Frei, E.; Arlt, V.; Stiborová, M.; Induction of cytochromes P450 1A1 and 1A2 suppresses formation of DNA adducts by carcinogenic aristolochic acid I in rats in vivo. Toxicology, 2016, Roč. 344, č. FEB 2016, s.7-18. IF 3.62 DOI: 10.1016/j.tox.2016.01.011

Lambry, J.; Stráňava, M.; Lobato, L.; Martínková, M.; Shimizu, T.; Liebl, U.; Vos, M.; Ultrafast Spectroscopy Evidence for Picosecond Ligand Exchange at the Binding Site of a Herne Protein: Heme-Based Sensor YddV. Journal of Physical Chemistry Letters, 2016, Roč. 7, č. 1, s.69-74. IF 7.45 DOI: 10.1021/acs.jpclett.5b02517

Heřmanová, I.; Arruabarrena-Aristorena, A.; Vališ, K.; Nuskova, H.; Alberich-Jorda, M.; Fišer, K.; Fernandez-Ruiz, S.; Kavan, D.; Pecinova, A.; Niso-Santano, M.; Žaliová, M.; Novák, P.; Houstek, J.; Mracek, T.; Kroemer, G.; Carracedo, A.; Trka, J.; Starková, J.; Pharmacological inhibition of fatty-acid oxidation synergistically enhances the effect of L-asparaginase in childhood ALL cells. Leukemia, 2016, Roč. 30, č. 1, s.209-218. IF 12.1 DOI: 10.1038/leu.2015.213

Machara, A.; Lux, V.; Kožíšek, M.; Grantz Šašková, K.; Štěpánek, O.; Kotora, M.; Parkan, K.; Pávová, M.; Glass, B.; Sehr, P.; Lewis, J.; Müller, B.; Kräusslich, H.; Konvalinka, J.; Specific Inhibitors of HIV Capsid Assembly Binding to the C-Terminal Domain of the Capsid Protein: Evaluation of 2-Arylquinazolines as Potential Antiviral Compounds. Journal of Medicinal Chemistry, 2016, Roč. 59, č. 2, s.545-558. IF 5.58 DOI: 10.1021/acs.jmedchem.5b01089

Stráňava, M.; Martínek, V.; Man, P.; Fojtíková, V.; Kavan, D.; Vaněk, O.; Shimizu, T.; Martínková, M.; Structural Characterization of the Heme-based Oxygen Sensor, AfGcHK, its Interactions with the Cognate Response Regulator, and their Combined Mechanism of Action in a Bacterial Two-component Signaling System. PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 2016, Roč. 84, č. 10, s.1375-1389. IF 2.49 DOI: 10.1002/prot.25083

Šácha, P.; Knedlík, T.; Schimer, J.; Tykvart, J.; Parolek, J.; Navrátil, V.; Dvořáková, P.; Sedlák, F.; Ulbrich, K.; Strohalm, J.; Majer, P.; Šubr, V.; Konvalinka, J.; iBodies: Modular Synthetic Antibody Mimetics Based on Hydrophilic Polymers Decorated with Functional Moieties. Angewandte Chemie - International Edition, 2016, Roč. 55, č. 7, s.2356-2360. IF 11.7 DOI: 10.1002/anie.201508642

Navrátil, M.; Tykvart, J.; Schimer, J.; Pachl, P.; Navrátil, V.; Rokob, TA.; Hlouchová, K.; Rulíšek, L.; Konvalinka, J.; Comparison of human glutamate carboxypeptidases II and III reveals their divergent substrate specificities. FEBS Journal, 2016, Roč. 283, č. 13, s.2528-2545. IF 4.23 DOI: 10.1111/febs.13761

Pompach, P.; Benada, O.; Rosůlek, M.; Darebná, P.; Hausner, J.; Růžička, V.; Volný, Novák, P.; Protein Chips Compatible with MALDI Mass Spectrometry Prepared by Ambient Ion Landing. Analytical Chemistry, 2016, Roč. 88, č. 17, s.8526-8534. IF 5.58 DOI: 10.1021/acs.analchem.6b01366

Stiborová, M.; Indra, R.; Moserová, M.; Frei, E.; Schmeiser, H.; Kopka, K.; Philips, D.; Arlt, V.; NADH:Cytochrome b(5) Reductase and Cytochrome b(5) Can Act as Sole Electron Donors to Human Cytochrome P450 1A1-Mediated Oxidation and DNA Adduct Formation by Benzo[a]pyrene. Chemical Research in Toxicology, 2016, Roč. 29, č. 8, s.1325-1334. IF 3.53 DOI: 10.1021/acs.chemrestox.6b00143

Synková, H.; Hýsková, V.; Garčeková, K.; Křížová, S.; Ryšlavá, H.; Protein as a sole source of nitrogen for in vitro grown tobacco plantlets. Biologia Plantarum, 2016, Roč. 60, č. 4, s.635-644. IF 1.66 DOI: 10.1007/s10535-016-0639-x

2015 (z celkového počtu 71)

Kukačka, Z.; Rosůlek, M.; Strohalm, M.; Kavan, D.; Novák, P.; Mapping protein structural changes by quantitative cross-linking. Methods, 2015, Roč. 89, č. 1 November 2015, s.112-120. IF 3.503 DOI: 10.1016/j.ymeth.2015.05.027

Pavlou, A.; Martínková, M.; Shimizu, T.; Kitanishi, K.; Stráňava, M.; Loullis, A.; Pinakoulaki, E.; Probing the ligand recognition and discrimination environment of the globin-coupled oxygen sensor protein YddV by FTIR and time-resolved step-scan FTIR spectroscopy. Physical Chemistry Chemical Physics, 2015, Roč. 17, č. 26, s.17007-17015. IF 4.449 DOI: 10.1039/c5cp01708d

Beyerle, J.; Frei, E.; Stiborová, M.; Habermann, N.; Ulrich, CM.; Biotransformation of xenobiotics in the human colon and rectum and its association with colorectal cancer. Drug Metabolism Reviews, 2015, Roč. 47, č. 2, s.199-221. IF 4.526 DOI: 10.3109/03602532.2014.996649

Hraběta, J.; Groh, T.; Abdel Rahman, MAK.; Poljaková, J.; Adam, V.; Kizek, R.; Uhlík, J.; Doktorová, H.; Černá, T.; Frei, E.; Stiborová, M.; Eckschlager, T.; Vacuolar-ATPase-mediated intracellular sequestration of ellipticine contributes to drug resistance in neuroblastoma cells. International Journal of Oncology, 2015, Roč. 47, č. 3, s.971-980. IF 3.018 DOI: 10.3892/ijo.2015.3066

Ječmen, T.; Ptáčková, R.; Černá, V.; Dračínská, H.; Hodek, P.; Stiborová, M.; Hudeček, J.; Šulc, M.; Photo-initiated crosslinking extends mapping of the protein-protein interface to membrane-embedded portions of cytochromes P450 2B4 and b5. Methods, 2015, Roč. 89, č. November 2015, s.128-137. IF 3.503 DOI: 10.1016/j.ymeth.2015.07.015

Stiborová, M.; Bárta, F.; Levová, K.; Hodek, P.; Schmeiser, HH.; Arlt, VM.; Martínek, V.; A Mechanism of O-Demethylation of Aristolochic Acid I by Cytochromes P450 and Their Contributions to This Reaction in Human and Rat Livers: Experimental and Theoretical Approaches. International Journal of Molecular Sciences, 2015, Roč. 16, č. 11, s.27561-27575. IF 3.257 DOI: 10.3390/ijms161126047

Stiborová, M.; Bárta, F.; Levová, K.; Hodek, P.; Frei, E.; Arlt, VM.; Schmeiser, HH.; The influence of ochratoxin A on DNA adduct formation by the carcinogen aristolochic acid in rats. Archives of Toxicology, 2015, Roč. 89, č. 11, s.2141-2158. IF 6.637 DOI: 10.1007/s00204-014-1360-1

Ryšlavá, H.; Pomeislová, A.; Pšondrová, Š.; Hýsková, V.; Smrček, S.; Phytoremediation of carbamazepine and its metabolite 10,11-epoxycarbamazepine by C3 and C4 plants. Environmental Science and Pollution Research, 2015, Roč. 22, č. 24, s.20271-20282. IF 2.760 DOI: 10.1007/s11356-015-5190-3

Ingr, M.; Lange, R.; Halabalová, V.; Yehya, A.; Hrnčiřík, J.; Chevalier-Lucia, D.; Palmade, L.; Blayo, C.; Konvalinka, J.; Dumay, E.; Inhibitor and Substrate Binding Induced Stability of HIV-1 Protease against Sequential Dissociation and Unfolding Revealed by High Pressure Spectroscopy and Kinetics. PLoS ONE, 2015, Roč. 10, č. 3, s.nestránkováno. IF 3.057 DOI: 10.1371/journal.pone.0119099

Schimer, J.; Pávová, M.; Anders, M.; Pachl, P.; Šácha, P.; Cígler, P.; Weber, J.; Majer, P.; Řezáčová, P.; Kraeusslich, H.; Mueller, B.; Konvalinka, J.; Triggering HIV polyprotein processing by light using rapid photodegradation of a tight-binding protease inhibitor. Nature Communications, 2015, Roč. 6, č. 09 March 2015, s.nestránkováno. IF 11.329 DOI: 10.1038/ncomms7461

Tykvart, J.; Schimer, J.; Jančařík, A.; Bařinková, J.; Navrátil, V.; Starková, J.; Šrámková, K.; Konvalinka, J.; Majer, P.; Šácha, P.; Design of Highly Potent Urea-Based, Exosite-Binding Inhibitors Selective for Glutamate Carboxypeptidase II. Journal of Medicinal Chemistry, 2015, Roč. 58, č. 10, s.4357-4363. IF 5.589 DOI: 10.1021/acs.jmedchem.5b00278

Yang, M.; Hoeppner, M.; Rey, M.; Kádek, A.; Man, P.; Schriemer, D.; Recombinant Nepenthesin II for Hydrogen/Deuterium Exchange Mass Spectrometry. Analytical Chemistry, 2015, Roč. 87, č. 13, s.6681-6687. IF 5.886 DOI: 10.1021/acs.analchem.5b00831

Kádek, A.; Kavan, D.; Felice, A.; Ludwig, R.; Halada, P.; Man, P.; Structural insight into the calcium ion modulated interdomain electron transfer in cellobiose dehydrogenase. FEBS Letters, 2015, Roč. 589, č. 11, s.1194-1199. IF 3.519 DOI: 10.1016/j.febslet.2015.03.029

Shimizu, T.; Huang, D.; Yan, F.; Stráňava, M.; Bartošová, M.; Fojtíková, V.; Martínková, M.; Gaseous O-2, NO, and CO in Signal Transduction: Structure and Function Relationships of Heme-Based Gas Sensors and Heme-Redox Sensors. Chemical Reviews, 2015, Roč. 115, č. 13, s.6491-6533. IF 37.369 DOI: 10.1021/acs.chemrev.5b00018

Lynn, G.; Laga, R.; Darrah, P.; Ishizuka, A.; Balaci, A.; Dulcey, A.; Pechar, M.; Pola, R.; Gerner, M.; Yamamoto, A.; Buechler, C.; Quinn, K.; Smelkinson, M.; Vaněk, O.; Cawood, R.; Hills, T.; Vasalatiy, O.; Kastenmueller, K.; Francica, J.; Stutts, L.; Tom, J.; Ryu, K.; Esser-Kahn, A.; Etrych, T.; Fisher, K.; Seymour, L.; Seder, R.; In vivo characterization of the physicochemical properties of polymer-linked TLR agonists that enhance vaccine immunogenicity. Nature Biotechnology, 2015, Roč. 33, č. 11, s.1201-U140. IF 43.113 DOI: 10.1038/nbt.3371

Hasan, S.; Osičková, A.; Bumba, L.; Novák, P.; Šebo, P.; Osička, R.; Interaction of Bordetella adenylate cyclase toxin with complement receptor 3 involves multivalent glycan binding. FEBS Letters, 2015, Roč. 589, č. 3, s.374-379. IF 3.519 DOI: 10.1016/j.febslet.2014.12.023

2014 (z celkového počtu 69)

Kádek, A.; Mrázek, H.; Halada, P.; Rey, M.; Schriemer, D.; Man, P.; Aspartic Protease Nepenthesin-1 as a Tool for Digestion in Hydrogen/Deuterium Exchange Mass Spectrometry. Analytical Chemistry, 2014, Roč. 86, č. 9, s.4287-4294. IF 5.825 DOI: 10.1021/ac404076j

Grantz Šašková, K.; Kožíšek, M.; Stray, K.; de Jong, D.; Řezáčová, P.; Brynda, J.; van Maarseveen, N.; Nijhuis, M.; Cihlář, T.; Konvalinka, J.; GS-8374, a Prototype Phosphonate-Containing Inhibitor of HIV-1 Protease, Effectively Inhibits Protease Mutants with Amino Acid Insertions. Journal of Virology, 2014, Roč. 88, č. 6, s.3586-3590. IF 4.648 DOI: 10.1128/JVI.02688-13

Kopecka, M.; Kosek, D.; Kukacka, Z.; Rezabkova, L.; Man, P.; Novak, P.; Obsil, T.; Obsilova, V.; Role of the EF-hand like motif in the 14-3-3 protein-mediated activation of yeast neutral trehalase Nth1. J. Biol. Chem., 2014, Roč. 289, s.13948-13961. IF 4.6 DOI: 10.1074/jbc.M113.544551

Anzenbacher, P.; Marchal, S.; Palacký, J.; Anzenbacherová, E.; Domaschke, T.; Lange, R.; Shimizu, T.; Kitanishi, K.; Stráňava, M.; Stiborová, M.; Martínková, M.; Pressure effects reveal that changes in the redox states of the heme iron complexes in the sensor domains of two heme-based oxygen sensor proteins, Ec DOS and YddV, have profound effects on their flexibility. FEBS Journal, 2014, Roč. 281, č. 23, s.5208-5219. IF 3.986 DOI: 10.1111/febs.13060

Stiborová, M.; Moserová, M.; Černá, V.; Indra, R.; Dračínský, M.; Šulc, M.; Henderson, C.; Wolf, C.; Schmeiser, H.; Phillips, D.; Frei, E.; Arlt, V.; Cytochronne b(5) and epoxide hydrolase contribute to benzo[a]pyrene-DNA adduct formation catalyzed by cytochrome P450 1A1 under low NADPH:P450 oxidoreductase conditions. Toxicology, 2014, Roč. 318, č. APR 6 2014, s.1-12. IF 3.745 DOI: 10.1016/j.tox.2014.02.002

Tykvart, J.; Navrátil, V.; Sedlák, F.; Corey, E.; Colombatti, M.; Fracasso, G.; Koukolík, F.; Bařinka, C.; Šácha, P.; Konvalinka, J.; Comparative analysis of monoclonal antibodies against prostate-specific membrane antigen (PSMA). Prostate, 2014, Roč. 74, č. 16, s.1674-1690. IF 3.566 DOI: 10.1002/pros.22887

Stiborová, M.; Levová, K.; Bárta, F.; Šulc, M.; Frei, E.; Arlt, V.; Schmeiser, H.; The influence of dicoumarol on the bioactivation of the carcinogen aristolochic acid I in rats. Mutagenesis, 2014, Roč. 29, č. 3, s.189-200. IF 3.497 DOI: 10.1093/mutage/geu004

Stiborová, M.; Schmeiser, HH.; Frei, E.; Hodek, P.; Martínek, V.; Enzymes Oxidizing the Azo Dye 1-Phenylazo-2-Naphthol (Sudan I) and their Contribution to its Genotoxicity and Carcinogenicity. Current Drug Metabolism, 2014, Roč. 15, č. 8, s.829-840. IF 3.487 DOI: 10.2174/1389200216666150206125442

Stráňava, M.; Martínková, M.; Stiborová, M.; Man, P.; Kitanishi, K.; Muchová, L.; Vítek, L.; Martínek, V.; Shimizu, T.; Introduction of water into the heme distal side by Leu65 mutations of an oxygen sensor, YddV, generates verdoheme and carbon monoxide, exerting the heme oxygenase reaction. Journal of Inorganic Biochemistry, 2014, Roč. 140, č. NOV 2014, s.29-38. IF 3.274 DOI: 10.1016/j.jinorgbio.2014.06.010

Jeřábek, P.; Florián, J.; Stiborová, M.; Martínek, V.; Flexible docking-based molecular dynamics/steered molecular dynamics calculations of protein-protein contacts in a complex of cytochrome P450 1A2 with cytochrome b5. Biochemistry, 2014, Roč. 53, č. 42, s.6695-6705. IF 3.194 DOI: 10.1021/bi500814t

Ryšlavá, H.; Valenta, R.; Hýsková, V.; Křížek, T.; Liberda, J.; Coufal, P.; Purification and enzymatic characterization of tobacco leaf β-N-acetylhexosaminidase. Biochimie, 2014, Roč. 107 Part B, č. December 2014, s.263-269. IF 3.123 DOI: 10.1016/j.biochi.2014.09.006

Hýsková, V.; Miedzińska, L.; Dobrá, J.; Vaňková, R.; Ryšlavá, H.; Phosphoenolpyruvate carboxylase, NADP-malic enzyme, and pyruvate, phosphate dikinase are involved in the acclimation of Nicotiana tabacum L. to drought stress. Journal of Plant Physiology, 2014, Roč. 171, č. 5, s.19-25. IF 2.77 DOI: 10.1016/j.jplph.2013.10.017

Bárta, F.; Levová, K.; Frei, E.; Schmeiser, H.; Arlt, V.; Stiborová, M.; The effect of aristolochic acid I on expression of NAD(P)H:quinone oxidoreductase in mice and rats-A comparative study. Mutation Research - Genetic Toxicology and Environmental Mutagenesis, 2014, Roč. 768, č. JUL 1 2014, s.1-7. IF 2.481 DOI: 10.1016/j.mrgentox.2014.01.012

Ptáčková, R.; Ječmen, T.; Novák, P.; Hudeček, J.; Stiborová, M.; Šulc, M.; The Application of an Emerging Technique for Protein-Protein Interaction Interface Mapping: The Combination of Photo-Initiated Cross-Linking Protein Nanoprobes with Mass Spectrometry. International Journal of Molecular Sciences, 2014, Roč. 15, č. 6, s.9224-9241. IF 2.339 DOI: 10.3390/ijms15069224

Dráb, T.; Kračmerová, J.; Hanzlíková, E.; Černá, T.; Litváková, R.; Pohlová, A.; Tichá, M.; Přikryl, P.; Liberda, J.; The antimicrobial action of histones in the reproductive tract of cow. Biochemical and Biophysical Research Communications, 2014, Roč. 443, č. 3, s.987-990. IF 2.281 DOI: 10.1016/j.bbrc.2013.12.077

Poljaková, J.; Groh, T.; Omaňa Gudiňo, Ž.; Hraběta, J.; Bořek Dohalská, L.; Kizek, R.; Doktorová, H.; Eckschlager, T.; Stiborová, M.; Hypoxia-mediated histone acetylation and expression of N-myc transcription factor dictate aggressiveness of neuroblastoma cells. Oncology Reports, 2014, Roč. 31, č. 4, s.1928-1934. IF 2.191 DOI: 10.3892/or.2014.2999

2013 (z celkového počtu 63)

Stiborová, M.; Dračínská, H.; Martínek, V.; Svášková, D.; Hodek, P.; Milichovský, J.; Hejduková, Ž.; Brotánek, J.; Schmeiser, H.; Frei, E.; Induced Expression of Cytochrome P450 1A and NAD(P)H:Quinone Oxidoreductase Determined at mRNA, Protein, and Enzyme Activity Levels in Rats Exposed to the Carcinogenic Azo Dye 1-Phenylazo-2-naphthol (Sudan I). Chemical Research in Toxicology, 2013, Roč. 26, č. 2, s.290-299. DOI: 10.1021/tx3004533

Mrázek, H.; Weignerová, L.; Bojarová, P.; Novák, P.; Vaněk, O.; Bezouška, K.; Carbohydrate synthesis and biosynthesis technologies for cracking of the glycan code: Recent advances. Biotechnology Advances, 2013, Roč. 31, č. 1, s.17-37. DOI: 10.1016/j.biotechadv.2012.03.008

Křížek, T.; Doubnerová, V.; Ryšlavá, H.; Coufal, P.; Bosáková, Z.; Offline and online capillary electrophoresis enzyme assays of beta-N-acetylhexosaminidase. Analytical and Bioanalytical Chemistry, 2013, Roč. 405, č. 8, s.2425-2434. DOI: 10.1007/s00216-012-6607-1

Pokorná, J.; Heyda, J.; Konvalinka, J.; Ion specific effects of alkali cations on the catalytic activity of HIV-1 protease. Faraday Discussions, 2013, Roč. 160, č. leden 2013, s.359-370. DOI: 10.1039/c2fd20094e

Rozbeský, D.; Sovová, Ž.; Marcoux, J.; Man, P.; Ettrich, R.; Robinson, C.; Novák, P.; Structural Model of Lymphocyte Receptor NKR-P1C Revealed by Mass Spectrometry and Molecular Modeling. Analytical Chemistry, 2013, Roč. 85, č. 3, s.1597-1604. DOI: 10.1021/ac302860m

Koberová, M.; Ječmen, T.; Šulc, M.; Černá, V.; Kizek, R.; Hudeček, J.; Stiborová, M.; Hodek, P.; Photo-cytochrome b(5) - A New Tool to Study the Cytochrome P450 Electron-transport Chain. International Journal of Electrochemical Science, 2013, Roč. 8, č. 1, s.125-134.

Vranová, I.; Moserová, M.; Hodek, P.; Kizek, R.; Frei, E.; Stiborová, M.; The Anticancer Drug Ellipticine Induces Cytochromes P450 1A1, 1A2 and 3A, Cytochrome b(5) and NADPH:Cytochrome P450 Oxidoreductase in Rat Liver, Kidney and Lung. International Journal of Electrochemical Science, 2013, Roč. 8, č. 2, s.1586-1597.

Poljaková, J.; Eckschlager, T.; Cinatl, J.; Kizek, R.; Frei, E.; Stiborová, M.; Electrochemical Determination of Enzymes Metabolizing Ellipticine in Thyroid Cancer Cells - a Tool to Explain the Mechanism of Ellipticine Toxicity to these Cells. International Journal of Electrochemical Science, 2013, Roč. 8, č. 2, s.1573-1585.

Hodek, P.; Trefil, P.; Šimůnek, J.; Hudeček, J.; Stiborová, M.; Optimized Protocol of Chicken Antibody (IgY) Purification Providing Electrophoretically Homogenous Preparations. International Journal of Electrochemical Science, 2013, Roč. 8, č. 1, s.113-124.

2012 (z celkového počtu 60)

Rozbeský, Daniel.; Man, Petr.; Kavan, Daniel.; Chmelík, Josef.; Černý, Jiří.; Bezouška, Karel.; Novák, Petr.; Chemical cross-linking and H/D exchange for fast refinement of protein crystal structure Analytical Chemistry, 2012, Roč. 84, č. 2 IF 5.856, s.867-870. DOI: 10.1021/ac202818m

Veselý, Filip.; Zolotarevová, Eva.; Špundová, Marcela.; Kaftan, Filip.; Šlouf, Miroslav.; Entlicher, Gustav.; Simple colorimetric methods for determination of sub-milligram amounts of ultrahigh molecular weight polyethylene wear particles Acta Biomaterialia, 2012, Roč. 8, č. 5 IF 4.865, s.1935-1938. DOI: 10.1016/j.actbio.2012.01.010

Čeřovská, Noemi.; Hoffmeisterová, Hana.; Moravec, Tomáš.; Plchová, Helena.; Folwarczna, Jitka.; Synková, Helena.; Ryšlavá, Helena.; Ludvíková, Viera.; Šmahel, Michal.; Transient expression of Human papillomavirus type 16 L2 epitope fused to N- and C-terminus of coat protein of Potato virus X in plants Journal of Biosciences, 2012, Roč. 37, č. 1 IF 1.648, s.125-133. DOI: 10.1007/s12038-011-9177-z

Haladová, Kateřina.; Mrázek, Hynek.; Ječmen, Tomáš.; Halada, Petr.; Man, Petr.; Novák, Petr.; Chmelík, Josef.; Obšil, Tomáš.; Šulc, Miroslav.; The combination of hydrogen/deuterium exchange or chemical cross-linking techniques with mass spectrometry: Mapping of human 14-3-3 zeta homodimer interface Journal of Structural Biology, 2012, Roč. 179, č. 1 IF 3.406, s.10-17. DOI: 10.1016/j.jsb.2012.04.016

Levová, Kateřina.; Moserová, Michaela.; Nebert, Daniel W..; Phillips, David H..; Frei, Eva.; Schmeiser, Heinz H..; Arlt, Volker M..; Stiborová, Marie.; NAD(P)H:quinone oxidoreductase expression in Cyp1a-knockout and CYP1A-humanized mouse lines and its effect on bioactivation of the carcinogen aristolochic acid I Toxicology and Applied Pharmacology, 2012, Roč. 265, č. 3 IF 4.447, s.360-367. DOI: 10.1016/j.taap.2012.09.004

Hlouchová, Klára.; Navrátil, Václav.; Tykvart, Jan.; Šácha, Pavel.; Konvalinka, Jan.; GCPII Variants, Paralogs and Orthologs Current Medicinal Chemistry, 2012, Roč. 19, č. 9 IF 4.859, s.1316-1322.

Stiborová, Marie.; Indra, Radek.; Moserová, Michaela.; Černá, Věra.; Rupertová, Martina.; Martínek, Václav.; Eckschlager, Tomáš.; Kizek, René.; Frei, Eva.; Cytochrome b(5) Increases Cytochrome P450 3A4-Mediated Activation of Anticancer Drug Ellipticine to 13-Hydroxyellipticine Whose Covalent Binding to DNA Is Elevated by Sulfotransferases and N,O-Acetyltransferases Chemical Research in Toxicology, 2012, Roč. 25, č. 5 IF 3.779, s.1075-1085. DOI: 10.1021/tx3000335

Naiman, Karel.; Dračínský, Martin.; Hodek, Petr.; Martínková, Markéta.; Schmeiser, Heinz H..; Frei, Eva.; Stiborová, Marie.; Formation, Persistence, and Identification of DNA Adducts Formed by the Carcinogenic Environmental Pollutant o-Anisidine in Rats Toxicological Sciences, 2012, Roč. 127, č. 2 IF 4.652, s.348-359. DOI: 10.1093/toxsci/kfs104

Kizek, René.; Adam, Vojtěch.; Hraběta, Jan.; Eckschlager, Tomáš.; Smutný, Svatopluk.; Burda, Jaroslav.; Frei, Eva.; Stiborová, Marie.; Anthracyclines and ellipticines as DNA-damaging anticancer drugs: Recent advances Pharmacology and Therapeutics, 2012, Roč. 133, č. 1 IF 8.562, s.26-39. DOI: 10.1016/j.pharmthera.2011.07.006

Stiborová, Marie.; Eckschlager, Tomáš.; Poljaková, Jitka.; Hraběta, Jan.; Adam, Vojtěch.; Kizek, René.; Frei, Eva.; The Synergistic Effects of DNA-Targeted Chemotherapeutics and Histone Deacetylase Inhibitors As Therapeutic Strategies for Cancer Treatment Current Medicinal Chemistry, 2012, Roč. 19, č. 25 IF 4.859, s.4218-4238.

Rajčanová, Michaela.; Tichá, Marie.; Kučerová, Zdenka.; Application of heptapeptides containing D-amino acid residues immobilized to magnetic particles and Sepharose for the study of binding properties of gastric aspartic proteases Journal of Separation Science, 2012, Roč. 35, č. 15 IF 2.733, s.1899-1905. DOI: 10.1002/jssc.201200221

Skálová, Tereza.; Kotýnková, Kristýna.; Dušková, Jarmila.; Hašek, Jindřich.; Koval, Tomáš.; Kolenko, Petr.; Novák, Petr.; Man, Petr.; Hanč, Pavel.; Vaněk, Ondřej.; Bezouška, Karel.; Dohnálek, Jan.; Mouse Clr-g, a Ligand for NK Cell Activation Receptor NKR-P1F: Crystal Structure and Biophysical Properties Journal of Immunology, 2012, Roč. 189, č. 10 IF 5.788, s.4881-4889. DOI: 10.4049/jimmunol.1200880

Stiborová, Marie.; Čechová, Tereza.; Bořek Dohalská, Lucie.; Moserová, Michaela.; Frei, Eva.; Schmeiser, Heinz H..; Páca, Jan.; Arlt, Volker M..; Activation and detoxification metabolism of urban air pollutants 2-nitrobenzanthrone and carcinogenic 3-nitrobenzanthrone by rat and mouse hepatic microsomes Neuroendocrinology Letters, 2012, Roč. 33, č. Suppl 3 IF 1.296, s.8-15.

Jeřábek, Petr.; Martínek, Václav.; Stiborová, Marie.; Theoretical investigation of differences in nitroreduction of aristolochic acid I by cytochromes P450 1A1, 1A2 and 1B1 Neuroendocrinology Letters, 2012, Roč. 33, č. Suppl 3 IF 1.296, s.25-32.

Šulc, Miroslav.; Ječmen, Tomáš.; Šnajdrová, Renata.; Novák, Petr.; Martínek, Václav.; Hodek, Petr.; Stiborová, Marie.; Hudeček, Jiří.; Mapping of interaction between cytochrome P450 2B4 and cytochrome b5: the first evidence of two mutual orientations Neuroendocrinology Letters, 2012, Roč. 33, č. Suppl 3 IF 1.296, s.41-47.

2011 (z celkového počtu 48)

Šulc, M.; Fadrhonsová, I.; Jelínková, M.; Chudomelová, M.; Felsberg, J.; Olšovská, J.; Determination of sibiromycin and its natural derivatives using new analytical and structural approaches Journal of Chromatography A, 2011, 1218(1), IF 4.194, s.83-91, DOI: 10.1016/j.chroma.2010.10.110

Ryšlavá, H.; Kalendová, A.; Doubnerová, V.; Skočdopol, P.; Kumar, V.; Kukačka, Z.; Pompach, P.; Vaněk, O.; Slámová, K.; Bojarová, P.; Kulik, N.; Ettrich, R.; Křen, V.; Bezouška, K.; Enzymatic characterization and molecular modeling of an evolutionarily interesting fungal beta-N-acetylhexosaminidase FEBS Journal, 2011, 278(14), IF 3.129, s.2469-2484, DOI: 10.1111/j.1742-4658.2011.08173.x

Dráb, T.; Kračmerová, J.; Tichá, I.; Hanzlíková, E.; Tichá, M.; Ryšlavá, H.; Doubnerová, V.; Maňásková-Postlerová, P.; Liberda, J.; Native Red Electrophoresis - A new method suitable for separation of native proteins Electrophoresis, 2011, 32(24), IF 3.569, s.3597-3599, DOI: 10.1002/elps.201100310

Plechanovová, A.; Byun, Y.; Alquicer, G.; Skultetyova, L.; Mlčochová, P.; Němcová, A.; Kim, H.; Navrátil, M.; Mease, R.; Lubkowski, J.; Pomper, M.; Konvalinka, J.; Rulíšek, L.; Bařinka, C.; Novel Substrate-Based Inhibitors of Human Glutamate Carboxypeptidase II with Enhanced Lipophilicity Journal of Medicinal Chemistry, 2011, 54(21), IF 5.207, s.7535-7546, DOI: 10.1021/jm200807m

Kotrbová, V.; Mrázová, B.; Moserová, M.; Martínek, V.; Hodek, P.; Hudeček, J.; Frei, E.; Stiborová, M.; Cytochrome b(5) shifts oxidation of the anticancer drug ellipticine by cytochromes P450 1A1 and 1A2 from its detoxication to activation, thereby modulating its pharmacological efficacy Biochemical Pharmacology, 2011, 82(6), IF 4.889, s.669-680, DOI: 10.1016/j.bcp.2011.06.003

Stiborová, M.; Mareš, J.; Frei, E.; Arlt, VM.; Martínek, V.; Schmeiser, HH.; The Human Carcinogen Aristolochic Acid I Is Activated to Form DNA Adducts by Human NAD(P)H:quinone Oxidoreductase Without the Contribution of Acetyltransferases or Sulfotransferases Environmental and Molecular Mutagenesis, 2011, 52(6), IF 3.493, s.448-459, DOI: 10.1002/em.20642

Pechar, M.; Pola, R.; Laga, R.; Ulbrich, K.; Bednárová, L.; Maloň, P.; Sieglová, I.; Král, V.; Fábry, M.; Vaněk, O.; Coiled Coil Peptides as Universal Linkers for the Attachment of Recombinant Proteins to Polymer Therapeutics Biomacromolecules, 2011, 12(10), IF 5.325, s.3645-3655, DOI: 10.1021/bm200897b

Levová, K.; Moserová, M.; Kotrbová, V.; Šulc, M.; Henderson, CJ.; Wolf, CR.; Phillips, DH.; Frei, E.; Schmeiser, HH.; Mareš, J.; Arlt,, VM.; Stiborová, M.; Role of Cytochromes P450 1A1/2 in Detoxication and Activation of Carcinogenic Aristolochic Acid I: Studies with the Hepatic NADPH:Cytochrome P450 Reductase Null (HRN) Mouse Model Toxicological Sciences, 2011, 121(1), IF 5.093, s.43-56, DOI: 10.1093/toxsci/kfr050

Arlt, VM.; Levová, K.; Bárta, F.; Shi, ZQ.; Evans, JD.; Frei, E.; Schmeiser, HH.; Nebert, DW.; Phillips, DH.; Stiborová, M.; Role of P450 1A1 and P450 1A2 in Bioactivation versus Detoxication of the Renal Carcinogen Aristolochic Acid I: Studies in Cyp1a1(-/-), Cyp1a2(-/-), and Cyp1a1/1a2(-/-) Mice Chemical Research in Toxicology, 2011, 24(10), IF 4.148, s.1710-1719, DOI: 10.1021/tx200259y

Kolenko, P.; Rozbeský, D.; Vaněk, O.; Kopecký, V.; Hofbauerová, K.; Novák, P.; Pompach, P.; Hašek, J.; Skálová, T.; Bezouška, K.; Dohnálek, J.; Molecular architecture of mouse activating NKR-P1 receptors Journal of Structural Biology, 2011, 175(3), IF 3.497, s.434-441, DOI: 10.1016/j.jsb.2011.05.001

Křížková, S.; Zítka, O.; Masařík, M.; Adam, V.; Stiborová, M.; Eckschlager, T.; Chavis, GJ.; Kizek, R.; Assays for determination of matrix metalloproteinases and their activity TrAC - Trends in Analytical Chemistry, 2011, 30(11), IF 6.602, s.1819-1832, DOI: 10.1016/j.trac.2011.06.016

2010 (z celkového počtu 40)

Renaudet, O.; Křenek, K.; Bossu, I.; Dumy, P.; Kádek, A.; Adámek, D.; Vaněk, O.; Kavan, D.; Gažák, R.; Šulc, M.; Bezouška, K.; Křen, V.; Synthesis of Multivalent Glycoconjugates Containing the Immunoactive LELTE Peptide: Effect of Glycosylation on Cellular Activation and Natural Killing by Human Peripheral Blood Mononuclear Cells Journal of the American Chemical Society, 2010, 132(19), IF 9.019, s.6800-6808, DOI: 10.1021/ja101296t

Adam, V.; Fabrik, I.; Eckschlager, T.; Stiborová, M.; Trnková, L.; Kizek, R.; Vertebrate metallothioneins as target molecules for analytical techniques. TrAC - Trends in Analytical Chemistry, 2010, 29(5), IF 6.602, s.409-418, DOI: 10.1016/j.trac.2010.02.004

Strohalm, M.; Kavan, D.; Novák, P.; Volný, M.; Havlíček, V.; mMass 3: A Cross-Platform Software Environment for Precise Analysis of Mass Spectrometric Data Analytical Chemistry, 2010, 82(11), IF 5.874, s.4648-4651, DOI: 10.1021/ac100818g

Rey, M.; Mrázek, H.; Pompach, P.; Novák, P.; Pelosi, L.; Brandolin, G.; Forest, E.; Havlíček, V.; Man, P.; Effective Removal of Nonionic Detergents in Protein Mass Spectrometry, Hydrogen/ Deuterium Exchange, and Proteomics Analytical Chemistry, 2010, 82(12), IF 5.874, s.5107-5116, DOI: 10.1021/ac100171m

Vidová, V.; Novák, P.; Strohalm, M.; Pól, J.; Havlíček, V.; Volný, M.; Laser Desorption-Ionization of Lipid Transfers: Tissue Mass Spectrometry Imaging without MALDI Matrix Analytical Chemistry, 2010, 82(12), IF 5.874, s.4994-4997, DOI: 10.1021/ac100661h

Kovalová, A.; Ledvina, M.; Šaman, D.; Zyka, D.; Kubíčková, M.; Žídek, L.; Sklenář, V.; Pompach, P.; Kavan, D.; Bílý, J.; Vaněk, O.; Kubínková, Z.; Libigerová, M.; Ivanová, Ľ.; Antolíková, E.; Mrázek, H.; Rozbeský, D.; Hofbauerová, K.; Křen, V.; Bezouška, K.; Synthetic N-Acetyl-D-glucosamine Based Fully Branched Tetrasaccharide, a Mimetic of the Endogenous Ligand for CD69, Activates CD69 Killer Lymphocytes upon Dimerization via a Hydrophilic Flexible Linker Journal of Medicinal Chemistry, 2010, 53(10), IF 5.207, s.4050-4065, DOI: 10.1021/jm100055b

Martínek, V.; Sklenář, J.; Dračínský, M.; Šulc, M.; Hofbauerová, K.; Bezouška, K.; Frei, E.; Stiborová, M.; Glycosylation Protects Proteins against Free Radicals Generated from Toxic Xenobiotics Toxicological Sciences, 2010, 2(16), IF 5.093, s.359-374, DOI: 10.1093/toxsci/kfq206

Martínková, E.; Maglott, A.; Leger, DY.; Bonnet, D.; Stiborová, M.; Takeda, K.; Martin, S.; Dontenwill, M.; alpha5beta1 integrin antagonists reduce chemotherapy-induced premature senescence and facilitate apoptosis in human glioblastoma cells. International Journal of Cancer, 2010, 127(5), IF 4.926, s.1240-1248, DOI: 10.1002/ijc.25187

Zolotarevová, E.; Entlicher, G.; Pavlová, E.; Šlouf, M.; Pokorný, D.; Veselý, F.; Gallo, J.; Sosna, A.; Distribution of polyethylene wear particles and bone fragments in periprosthetic tissue around total hip joint replacements Acta Biomaterialia, 2010, 6(9), IF 4.822, s.3595-3600, DOI: 10.1016/j.actbio.2010.04.010

Novotná, L.; Emmerová, T.; Horák, D.; Kučerová, Z.; Tichá, M.; Iminodiacetic acid-modified magnetic poly(2-hydroxyethyl methacrylate)-based microspheres for phosphopeptide enrichment Journal of Chromatography A, 2010, 1217(51), IF 4.194, s.8032-8040, DOI: 10.1016/j.chroma.2010.08.058

Stiborová, M.; Martínek, V.; Svobodová, M.; Šístková, J.; Dvořák, Z.; Ulrichová, J.; Šimánek, V.; Frei, E.; Schmeiser, HH.; Phillips, DH.; Arlt, VM.; Mechanisms of the different DNA adduct forming potentials of the urban air pollutants 2-nitrobenzanthrone and carcinogenic 3-nitrobenzanthrone Chemical Research in Toxicology, 2010, 23(7), IF 4.148, s.1192-1201, DOI: 10.1021/tx100052d

Černý, M.; Doubnerová, V.; Müller, K.; Ryšlavá, H.; Characterization of phosphoenolpyruvate carboxylase from mature maize seeds: Properties of phosphorylated and dephosphorylated forms. Biochimie, 2010, 92(10), IF 3.787, s.1362-1370, DOI: 10.1016/j.biochi.2010.06.019

Fanfrlík, J.; Bronowska, AK.; Řezáč, J.; Přenosil, O.; Konvalinka, J.; Hobza, P.; A reliable docking/scoring scheme based on the semiempirical quantum mechanical PM6-DH2 method accurately covering dispersion and H-bonding: HIV-1 protease with 22 ligands. Journal of Physical Chemistry B, 2010, 114(19), IF 3.603, s.12666-12678, DOI: 10.1021/jp1032965

Zolotarevová, E.; Hudeček, J.; Špundová, M.; Entlicher, G.; Binding of proteins to ultra high molecular weight polyethylene wear particles as a possible mechanism of macrophage and lymphocyte activation Journal of Biomedical Materials Research - Part A, 2010, 95(3), IF 3.044, s.950-955, DOI: 10.1002/jbm.a.32924

2009 (z celkového počtu 43)

Martínková, L.; Vejvoda, V.; Kaplan, O.; Kubáč, D.; Malandra, A.; Cantarella, M.; Bezouška, K.; Křen, V.; Fungal nitrilases as biocatalysts: Recent developments Biotechnology advances, 2009, 27(6), IF 8.250, s.661-670 http://dx.doi.org/10.1016/j.biotechadv.2009.04.027

Grantz Šašková, K.; Kožíšek, M.; Řezáčová, P.; Brynda, J.; Yashina, T.; Kagan, R.; Konvalinka, J.; Molecular Characterization of Clinical Isolates of Human Immunodeficiency Virus Resistant to the Protease Inhibitor Darunavir Journal of Virology, 2009, 83(17), IF 5.150, s.8810-8818 http://dx.doi.org/10.1128/JVI.00451-09

Schmeiser, H.; Stiborová, M.; Arlt, V.; Chemical and molecular basis of the carcinogenicity of Aristolochia plants Current opinion in drug discovery & development, 2009, 12(1), IF 4.904, s.141-148

Hoffman, H.; Jirásková, J.; Cígler, P.; Šanda, M.; Schraml, J.; Konvalinka, J.; Hydroxamic acids as a novel family of serine racemase inhibitors: Mechanistic analysis reveals different modes of interaction with the pyridoxal-5'-phosphate cofactor Journal of Medicinal Chemistry, 2009, 52(19), IF 4.802, s.6032-6041 http://dx.doi.org/10.1021/jm900775q

Poljaková, J.; Eckschlager, T.; Hraběta, J.; Hřebačková, J.; Smutný, S.; Frei, E.; Martínek, V.; Kizek, R.; Stiborová, M.; The mechanism of cytotoxicity and DNA adduct formation by the anticancer drug ellipticine in human neuroblastoma cells Biochemical Pharmacology, 2009, 77(9), IF 4.254, s.1466-1479 http://dx.doi.org/10.1016/j.bcp.2009.01.021

Heyda, J.; Pokorná, J.; Vrbka, L.; Vácha, R.; Jagoda-Cwiklik, B.; Konvalinka, J.; Jungwirth, P.; Vondrášek, J.; Ion specific effects of sodium and potassium on the catalytic activity of HIV-1 protease Physical chemistry chemical physics, 2009, 11(35), IF 4.116, s.7599-7604 http://dx.doi.org/10.1039/b905462f

Dračínský, M.; Cvačka, J.; Semanská, M.; Martínek, V.; Frei, E.; Stiborová, M.; Mechanism of formation of (deoxy)guanosine adducts derived from peroxidase-catalyzed oxidation of the carcinogenic nonaminoazo dye 1-phenylazo-2-hydroxynaphthalene (Sudan I) Chemical Research in Toxicology, 2009, 22(11), IF 3.740, s.1765-1773 http://dx.doi.org/10.1021/tx900201q

Balková, P.; Ježková, J.; Hlaváčková, M.; Neckář, J.; Staňková, B.; Kolář, F.; Novák, F.; Nováková, O.; Dietary polyunsaturated fatty acids and adaptation to chronic hypoxia alter acyl composition of serum and heart lipids British Journal of Nutrition, 2009, 102(9), IF 3.446, s.1297-1307 http://dx.doi.org/10.1017/S0007114509389242

Pompach, P.; Man, P.; Kavan, D.; Hofbauerová, K.; Kumar, V.; Bezouška, K.; Havlíček, V.; Novák, P.; Modified electrophoretic and digestion conditions allow a simplified mass spectrometric evaluation of disulfide bonds. Journal of Mass Spectrometry, 2009, 44(11), IF 3.411, s.1571-1578 http://dx.doi.org/10.1002/jms.1609

Klusák, V.; Bařinka, C.; Plechanovová, A.; Mlčochová, P.; Konvalinka, J.; Rulíšek, L.; Lubkowski, J.; Reaction mechanism of glutamate carboxypeptidase II revealed by mutagenesis, X-ray crystallography and computational methods Biochemistry, 2009, 48(19), IF 3.226, s.4126-4138 http://dx.doi.org/10.1021/bi900220s

Mlčochová, P.; Bařinka, C.; Tykvart, J.; Šácha, P.; Konvalinka, J.; Prostate-specific membrane antigen and its truncated form PSM' Prostate, 2009, 69(5), IF 3.081, s.471-479 http://dx.doi.org/10.1002/pros.20894

Hlouchová, K.; Bařinka, C.; Konvalinka, J.; Lubkowski, J.; Structural insight into the evolutionary and pharmacologic homology of glutamate carboxypeptidases II and III FEBS JOURNAL, 2009, 276(16), IF 3.042, s.4448-4462 http://dx.doi.org/10.1111/j.1742-4658.2009.07152.x

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